Literature DB >> 29484493

Secondary sclerosing cholangitis in critically ill patients after a traffic accident-a new entity that should be considered in death classification.

Fred Zack1, Horst Nizze1, Verena Blaas1, Anne Port1, Andreas Büttner2.   

Abstract

A 49-year-old female sustained a polytrauma after being hit by a vehicle in a traffic accident. Following the incident, the woman had various surgical interventions and underwent intensive care over a 6-week period. Eight months later, she died after developing secondary sclerosing cholangitis (SSC). Autopsy revealed liver failure and hepatic encephalopathy due to SSC caused by the polytrauma and the subsequent intensive care. Prior to the accident, there was no evidence of a pre-existing liver or biliary system disease. The death of the patient was classified as non-natural as a causal consequence of the traffic accident. SSC has been clinically described as a complication of intensive care. Since it has a high mortality rate, it is important that forensics and pathologists are aware of the condition.

Entities:  

Keywords:  Causal link; Intensive care; Liver failure; Non-natural death; Secondary sclerosing cholangitis in the critically ill patient (SSC-CIP); Traffic accident

Mesh:

Year:  2018        PMID: 29484493     DOI: 10.1007/s00414-018-1801-0

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  14 in total

1.  Secondary sclerosing cholangitis after intensive care unit treatment: clues to the histopathological differential diagnosis.

Authors:  Irene Esposito; Andrea Kubisova; Adolf Stiehl; Hasan Kulaksiz; Peter Schirmacher
Journal:  Virchows Arch       Date:  2008-09-04       Impact factor: 4.064

2.  Secondary sclerosing cholangitis after long-term treatment in an intensive care unit: clinical presentation, endoscopic findings, treatment, and follow-up.

Authors:  C Jaeger; G Mayer; R Henrich; L Gossner; T Rabenstein; A May; E Guenter; C Ell
Journal:  Endoscopy       Date:  2006-07       Impact factor: 10.093

3.  What are the differences in injury patterns of young and elderly traffic accident fatalities considering death on scene and death in hospital?

Authors:  Daniela Heinrich; Christopher Holzmann; Anja Wagner; Anja Fischer; Roman Pfeifer; Matthias Graw; Sylvia Schick
Journal:  Int J Legal Med       Date:  2017-02-08       Impact factor: 2.686

Review 4.  Sclerosing cholangitis: a focus on secondary causes.

Authors:  Rupert Abdalian; E Jenny Heathcote
Journal:  Hepatology       Date:  2006-11       Impact factor: 17.425

5.  Sclerosing cholangitis following severe trauma: description of a remarkable disease entity with emphasis on possible pathophysiologic mechanisms.

Authors:  Johannes Benninger; Rainer Grobholz; Yurdaguel Oeztuerk; Christoph H Antoni; Eckhart G Hahn; Manfred V Singer; Richard Strauss
Journal:  World J Gastroenterol       Date:  2005-07-21       Impact factor: 5.742

6.  Outcome of patients with ischemic-like cholangiopathy with secondary sclerosing cholangitis after liver transplantation.

Authors:  Gabi I Kirchner; Marcus N Scherer; Aiman Obed; Petra Ruemmele; Reiner Wiest; Matthias Froh; Martin Loss; Hans-Juergen Schlitt; Juergen Schölmerich; Cornelia M Gelbmann
Journal:  Scand J Gastroenterol       Date:  2010-11-30       Impact factor: 2.423

7.  Secondary sclerosing cholangitis following major burn.

Authors:  Ziv Ben-Ari; David Levingston; Ella Weitzman; Yael Haviv-Yadid; Oranit Cohen-Ezra; Peretz Weiss; Eli Zuckerman; Yael Inbar; Michal Amitai; Uri Rimon; Maya Goder; Josef Haik
Journal:  Ann Hepatol       Date:  2015 Sep-Oct       Impact factor: 2.400

8.  Progressive sclerosing cholangitis after septic shock: a new variant of vanishing bile duct disorders.

Authors:  S Engler; C Elsing; C Flechtenmacher; L Theilmann; W Stremmel; A Stiehl
Journal:  Gut       Date:  2003-05       Impact factor: 23.059

9.  Poor outcome in progressive sclerosing cholangitis after septic shock.

Authors:  H Kulaksiz; D Heuberger; S Engler; A Stiehl
Journal:  Endoscopy       Date:  2008-02-11       Impact factor: 10.093

Review 10.  Secondary sclerosing cholangitis in critically ill patients: current perspectives.

Authors:  Hafsteinn O Gudnason; Einar S Björnsson
Journal:  Clin Exp Gastroenterol       Date:  2017-06-23
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  1 in total

Review 1.  Secondary Sclerosing Cholangitis in Critically Ill Patients: An Underdiagnosed Entity.

Authors:  Pedro Martins; Mariana Verdelho Machado
Journal:  GE Port J Gastroenterol       Date:  2019-07-30
  1 in total

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