| Literature DB >> 29483259 |
Liang Zhang1,2, Vanesa Marcos2, David A Leigh3,2.
Abstract
The widespread use of molecular-level motion in key natural processes suggests that great rewards could come from bridging the gap between the present generation of synthetic molecular machines-which by and large function as switches-and the machines of the macroscopic world, which utilize the synchronized behavior of integrated components to perform more sophisticated tasks than is possible with any individual switch. Should we try to make molecular machines of greater complexity by trying to mimic machines from the macroscopic world or instead apply unfamiliar (and no doubt have to discover or invent currently unknown) mechanisms utilized by biological machines? Here we try to answer that question by exploring some of the advances made to date using bio-inspired machine mechanisms.Keywords: catenanes; molecular machines; molecular motors; molecular robotics; rotaxanes
Year: 2018 PMID: 29483259 PMCID: PMC6156679 DOI: 10.1073/pnas.1712788115
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205