| Literature DB >> 29482203 |
Jorik Nonnekes1,2, Nathalie Benda2, Hanneke van Duijnhoven1, Frits Lem2, Noël Keijsers3, Jan Willem K Louwerens4, Allan Pieterse1, Bertjo Renzenbrink5, Vivian Weerdesteyn1,3, Jaap Buurke6,7, Alexander C H Geurts1,2.
Abstract
Importance: Gait impairments are common in patients with chronic supratentorial upper motor neuron lesions and are a source of disability. Clinical management aimed at improving the gait pattern in these patients is generally perceived as a challenging task because many possible abnormalities may interact. Moreover, a multitude of treatment options exist, ranging from assistive devices and muscle stretching to pharmacologic and surgical interventions, but evidence is inconclusive for most approaches and clear treatment guidelines are lacking. Observations: Gait deviations in adults with a chronic supratentorial upper motor neuron lesion can approximately be reduced to the following 3 groups of primary deficits: (1) imbalance of muscle strength, length, and activity around the ankle and tarsal joints leading to pes equinovarus or pes equinus; (2) calf muscle weakness; and (3) overactivity of proximal leg muscles. Conclusions and Relevance: A stepwise treatment algorithm emphasizes medical-technical interventions, which are based on evidence when available and otherwise reflect practice-based experience.Entities:
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Year: 2018 PMID: 29482203 DOI: 10.1001/jamaneurol.2017.5041
Source DB: PubMed Journal: JAMA Neurol ISSN: 2168-6149 Impact factor: 18.302