Amy L Deckert1, Galina Gheihman2, Rinat Nissim3, Cynthia Chung4, Aaron D Schimmer5, Camilla Zimmermann6, Gary Rodin7. 1. Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 2M9, Canada; Global Institute of Psychosocial, Palliative and End-of-Life Care (GIPPEC), University of Toronto and University Health Network, Toronto, Ontario, M5G 1Z6, Canada. Electronic address: amy.deckert@uhn.ca. 2. Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, United States. 3. Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 2M9, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, M5T 1R8, Canada. 4. Department of Rehabilitation Services, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 2M9, Canada. 5. Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 2M9, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, M5G 1L7, Canada. 6. Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 2M9, Canada; Global Institute of Psychosocial, Palliative and End-of-Life Care (GIPPEC), University of Toronto and University Health Network, Toronto, Ontario, M5G 1Z6, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, M5S 1A8, Canada. 7. Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 2M9, Canada; Global Institute of Psychosocial, Palliative and End-of-Life Care (GIPPEC), University of Toronto and University Health Network, Toronto, Ontario, M5G 1Z6, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, M5T 1R8, Canada.
Abstract
PURPOSE: The symptom burden of acute myeloid leukemia (AML) and its treatment can accelerate physical deconditioning and impair mobility and quality of life. In the present study, we explore the subjective experience of functional capacity in people living with AML. METHODS: A secondary qualitative analysis was performed on a subset of interviews (n = 21) obtained from an observational cohort study of people with acute leukemia. Conventional content analysis was employed to identify key themes and concepts. RESULTS: Participants valued their physical function to the extent that it was required to pursue personally meaningful activities and interests. We identified Meaningful Activity as an overarching goal of participants. Three interrelated themes captured the obstacles participants reported facing when attempting to realize this goal: Compromised Body, Threatened Identity, and Shrinking World. Adaptation was common across themes, representing the strategies employed to overcome such challenges. Themes were consistent across participants, despite the variability in disease states at the time of the interview. CONCLUSIONS: Dynamic interactions between physical, psychological, and environmental factors affect the pursuit and achievement of meaningful activity among people living with AML. It may be important to consider personal incentives when designing interventions for physical rehabilitation in this patient population.
PURPOSE: The symptom burden of acute myeloid leukemia (AML) and its treatment can accelerate physical deconditioning and impair mobility and quality of life. In the present study, we explore the subjective experience of functional capacity in people living with AML. METHODS: A secondary qualitative analysis was performed on a subset of interviews (n = 21) obtained from an observational cohort study of people with acute leukemia. Conventional content analysis was employed to identify key themes and concepts. RESULTS:Participants valued their physical function to the extent that it was required to pursue personally meaningful activities and interests. We identified Meaningful Activity as an overarching goal of participants. Three interrelated themes captured the obstacles participants reported facing when attempting to realize this goal: Compromised Body, Threatened Identity, and Shrinking World. Adaptation was common across themes, representing the strategies employed to overcome such challenges. Themes were consistent across participants, despite the variability in disease states at the time of the interview. CONCLUSIONS: Dynamic interactions between physical, psychological, and environmental factors affect the pursuit and achievement of meaningful activity among people living with AML. It may be important to consider personal incentives when designing interventions for physical rehabilitation in this patient population.
Authors: Thomas W LeBlanc; Nigel H Russell; Loriana Hernandez-Aldama; Charlotte Panter; Timothy J Bell; Verna Welch; Diana Merino Vega; Louise O'Hara; Julia Stein; Melissa Barclay; Francois Peloquin; Andrew Brown; Jasmine Healy; Lucy Morgan; Adam Gater; Ryan Hohman; Karim Amer; Dawn Maze; Roland B Walter Journal: Oncol Ther Date: 2022-06-13
Authors: Thuy T Koll; Jessica N Semin; Rachel A Coburn; Diane M Hill-Polerecky; Kimberly A Miller; Tanya M Wildes; Paul A Estabrooks; Katherine J Jones Journal: J Geriatr Oncol Date: 2019-12-11 Impact factor: 3.599