Literature DB >> 29479508

Optimization of silver nanoparticles biosynthesis mediated by Aspergillus niger NRC1731 through application of statistical methods: enhancement and characterization.

Maysa A Elsayed1, Abdelmageed M Othman1, Mohamed M Hassan1, Ali M Elshafei1.   

Abstract

The fungal-mediated silver nanoparticles (AgNPs) biosynthesis optimization via the application of central composite design (CCD) response surface to develop an effective ecofriendly and inexpensive green process was the aim of the current study. Nanosilver biosynthesis using the Aspergillus niger NRC1731 cell-free filtrate (CFF) was studied through involving the most parameters affecting the AgNPs green synthesis and its interactions effects. The statistical optimization models showed that using 59.37% of CFF in reaction containing 1.82 mM silver nitrate for 34 h at pH 7.0 is the optimum value to optimize the AgNPs biosynthesis. The obtained AgNPs were characterized by means of electron microscopy, UV/visible spectrophotometry, energy dispersive X-ray analysis and infrared spectroscopy to elucidate its almost spherical shape with diameter of 3-20 nm. The produced AgNPs exhibited a considerable antimicrobial activity against Bacillus mycoides, Escherichia coli in addition to Candida albicans.

Entities:  

Keywords:  Aspergillus niger; Biosynthesis; Characterization; Nanosilver; Optimization

Year:  2018        PMID： 29479508      PMCID： PMC5814388          DOI： 10.1007/s13205-018-1158-6

Source DB:  PubMed          Journal:  3 Biotech        ISSN： 2190-5738            Impact factor:   2.406


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3.  Mycosynthesis, Characterization, and Mosquitocidal Activity of Silver Nanoparticles Fabricated by Aspergillus niger Strain.

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