Literature DB >> 29479202

Variations and similarities in clinical management of neonatal abstinence syndrome: Findings of a Canadian survey.

Katie Murphy1, Helen Coo1, Ruth Warre2, Vibhuti Shah3, Kimberly Dow1.   

Abstract

BACKGROUND: There are no evidence-based national guidelines for managing neonatal abstinence syndrome (NAS) and surveys from other countries have demonstrated considerable variations in practice.
OBJECTIVE: To describe NAS management practices in Canada.
METHOD: The directors of all Level 2 and Level 3 neonatal intensive care units (NICUs) were contacted to request their participation in a structured telephone survey. Frequency distributions were generated and associations between practice variations and unit type (Level 2 or 3) and size were examined.
RESULTS: Personnel at 65 of 103 sites (63.1%) participated. Most (92.3%) stated their hospital has a written NAS practice guideline. The majority (89.5%) use a version of Finnegan's scoring system to monitor signs. If pharmacological treatment is required, 89.2% admit infants to the NICU and 93.8% routinely use cardiorespiratory monitors when treatment is initiated. Morphine is the first-line medication at most sites (96.9%). There was greater variability in terms of other practices: 44.6% observe at-risk infants in the NICU, while 52.3% allow them to room-in with their mothers; 65.1% use adjunct medications; 36.9% and 38.9% will discharge infants on the first-line and adjunct medications respectively, and 53.8% reported that breastfeeding is always encouraged, while 44.6% discourage breastfeeding if the mother continues to use illicit drugs and 1.5% make recommendations on an individual basis. Few practice variations were associated with unit type or size.
CONCLUSION: While most NICUs surveyed have an NAS practice guideline, there are some notable differences in how NAS is managed. This underscores the need for research that can be translated into best practices.

Entities:  

Keywords:  Canada; Infant; Management; Neonatal abstinence syndrome; Neonatal intensive care unit; Newborn.

Year:  2017        PMID: 29479202      PMCID: PMC5804777          DOI: 10.1093/pch/pxx054

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN: 1205-7088            Impact factor:   2.253


  14 in total

1.  A survey of the management of neonatal opiate withdrawal in England and Wales.

Authors:  C L Morrison; C Siney
Journal:  Eur J Pediatr       Date:  1996-04       Impact factor: 3.183

2.  Neonatal opioid withdrawal and antenatal opioid prescribing.

Authors:  Suzanne D Turner; Tara Gomes; Ximena Camacho; Zhan Yao; Astrid Guttmann; Muhammad M Mamdani; David N Juurlink; Irfan A Dhalla
Journal:  CMAJ Open       Date:  2015-01-13

3.  Neonatal abstinence syndrome: transitioning methadone-treated infants from an inpatient to an outpatient setting.

Authors:  C H Backes; C R Backes; D Gardner; C A Nankervis; P J Giannone; L Cordero
Journal:  J Perinatol       Date:  2011-08-18       Impact factor: 2.521

4.  SOGC clinical practice guidelines: Substance use in pregnancy: no. 256, April 2011.

Authors:  Suzanne Wong; Alice Ordean; Meldon Kahan
Journal:  Int J Gynaecol Obstet       Date:  2011-08       Impact factor: 3.561

5.  Management of neonatal abstinence syndrome in neonatal intensive care units: a national survey.

Authors:  S Sarkar; S M Donn
Journal:  J Perinatol       Date:  2006-01-01       Impact factor: 2.521

6.  A National Survey of the Nursing Care of Infants With Prenatal Substance Exposure in Canadian NICUs.

Authors:  Lenora Marcellus; Tara Loutit; Shannon Cross
Journal:  Adv Neonatal Care       Date:  2015-10       Impact factor: 1.968

7.  Neonatal abstinence syndrome--postnatal ward versus neonatal unit management.

Authors:  Tolulope Saiki; Silke Lee; Simon Hannam; Anne Greenough
Journal:  Eur J Pediatr       Date:  2009-05-14       Impact factor: 3.183

Review 8.  Neonatal abstinence syndrome: essentials for the practitioner.

Authors:  Anita Siu; Christine A Robinson
Journal:  J Pediatr Pharmacol Ther       Date:  2014-07

9.  Rooming-in compared with standard care for newborns of mothers using methadone or heroin.

Authors:  Ronald R Abrahams; S Ann Kelly; Sarah Payne; Paul N Thiessen; Jessica Mackintosh; Patricia A Janssen
Journal:  Can Fam Physician       Date:  2007-10       Impact factor: 3.275

10.  Rooming-in for Infants at Risk of Neonatal Abstinence Syndrome.

Authors:  Sarah McKnight; Helen Coo; Gregory Davies; Belinda Holmes; Adam Newman; Lynn Newton; Kimberly Dow
Journal:  Am J Perinatol       Date:  2015-11-20       Impact factor: 1.862

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  4 in total

1.  Neonatal abstinence syndrome - a better way.

Authors:  Paul Thiessen
Journal:  Paediatr Child Health       Date:  2018-07-09       Impact factor: 2.253

2.  The ACT NOW Clinical Practice Survey: Gaps in the Care of Infants With Neonatal Opioid Withdrawal Syndrome.

Authors:  Jessica N Snowden; A Akshatha; Robert D Annett; Margaret M Crawford; Abhik Das; Lori A Devlin; Rosemary D Higgins; Zhuopei Hu; Elizabeth Lindsay; Stephanie Merhar; Clare Campbell Nesmith; Heather Pratt-Chavez; Judith Ross; Alan E Simon; M Cody Smith; Christine B Turley; Anita Walden; Leslie Young; Bonny Whalen
Journal:  Hosp Pediatr       Date:  2019-07-19

3.  Post-discharge healthcare utilization in infants with neonatal opioid withdrawal syndrome.

Authors:  Shikhar Shrestha; Melissa H Roberts; Jessie R Maxwell; Lawrence M Leeman; Ludmila N Bakhireva
Journal:  Neurotoxicol Teratol       Date:  2021-03-23       Impact factor: 4.071

4.  Outcome reporting in neonates experiencing withdrawal following opioid exposure in pregnancy: a systematic review.

Authors:  Flora Shan; Sonya MacVicar; Karel Allegaert; Martin Offringa; Lauren M Jansson; Sarah Simpson; Wendy Moulsdale; Lauren E Kelly
Journal:  Trials       Date:  2020-03-12       Impact factor: 2.279

  4 in total

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