| Literature DB >> 29477281 |
Abstract
Bile acids facilitate dietary fat absorption upon release into the small intestine after a meal. A recent study by Liu and colleagues identifies a gut-brain axis wherein bile acids signal an energy-replete state to hypothalamic AgRP neurons via activation of neuronal FGF receptors, which orchestrate whole-body glucose metabolism.Entities:
Keywords: AgRP neurons; bile acids; fibroblast growth factors; glucose metabolism; hypothalamus
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Year: 2018 PMID： 29477281 DOI： 10.1016/j.tem.2018.02.001
Source DB: PubMed Journal: Trends Endocrinol Metab ISSN： 1043-2760 Impact factor: 12.015