| Literature DB >> 29476812 |
Aristides Bezerra de Melo1, William Marciel de Souza2, Gustavo Olszanski Acrani3, Valéria Lima Carvalho1, Marilia Farignoli Romeiro4, Aline Lavado Tolardo4, Sandro Patroca da Silva5, Jedson Ferreira Cardoso5, Jannifer de Oliveira Chiang1, João Lídio da Silva Gonçalves Vianez5, Raimunda do Socorro da Silva Azevedo1, Luiz Tadeu Moraes Figueiredo4, Pedro Fernando da Costa Vasconcelos1, Márcio Roberto Teixeira Nunes5, Daniele Barbosa de Almeida Medeiros6.
Abstract
Tacaiuma virus (TCMV) is antigenically characterized as a member of the Anopheles A complex in the Orthobunyavirus genus, Peribunyaviridae family (Bunyavirales order). Clinically, the TCMV infection is characterized by acute febrile illness with myalgia and arthralgia lasting three to five days. However, the genomic and evolutionary aspect of this virus has not been elucidated. In this study, we described the complete coding sequences of three segments of two TCMV strains isolated in Brazil and three complete coding sequences of the small segment of three TCMV strains. All the strains sequenced in this study showed the typical genomic organization of orthobunyaviruses that infect vertebrates, except for the absence of the open reading frame that encodes the well-described non-structural small protein. This study presents the genomic and evolutionary characterization of TCMV strains and would be helpful for diagnostic purposes and epidemiology.Entities:
Keywords: Arbovirus; Bunyavirales; Genomic characterization; Orthobunyavirus; Tacaiuma orthobunyavirus
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Year: 2018 PMID： 29476812 DOI： 10.1016/j.meegid.2018.02.027
Source DB: PubMed Journal: Infect Genet Evol ISSN： 1567-1348 Impact factor: 3.342