Literature DB >> 29476322

Radiotherapy in soft-tissue sarcoma of the extremities.

R Correa1, J Gómez-Millán2, M Lobato2, A Fernández2, R Ordoñez2, C Castro2, Y Lupiañez2, J A Medina2.   

Abstract

Sarcomas are an infrequent and heterogeneous group of neoplasia. Surgery with or without associated radiotherapy (RT) is the basic treatment for this type of tumour. To increase the therapeutic ratio (the index between cytotoxic effects in tumours and normal tissue complications with a certain dose of radiation), new advances are being investigated to increase local and distant control and to decrease the morbidity of the treatment. The aim of this review was to analyse the different strategies, based on technology and biology, which are being investigated to increase the therapeutic ratio of this disease.

Entities:  

Keywords:  Chemotherapy; Conservative surgery; Multikinase inhibitor; Postoperative radiotherapy; Preoperative radiotherapy; Soft-tissue sarcoma

Mesh:

Substances:

Year:  2018        PMID: 29476322     DOI: 10.1007/s12094-018-1848-x

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  54 in total

1.  Radiological and pathological response following pre-operative radiotherapy for soft-tissue sarcoma.

Authors:  David Roberge; Tanya Skamene; Ayoub Nahal; Robert E Turcotte; Tom Powell; Carolyn Freeman
Journal:  Radiother Oncol       Date:  2010-10-30       Impact factor: 6.280

2.  Long-term results of Phase II study of high dose photon/proton radiotherapy in the management of spine chordomas, chondrosarcomas, and other sarcomas.

Authors:  Thomas F DeLaney; Norbert J Liebsch; Frank X Pedlow; Judith Adams; Elizabeth A Weyman; Beow Y Yeap; Nicolas Depauw; G Petur Nielsen; David C Harmon; Sam S Yoon; Yen-Lin Chen; Joseph H Schwab; Francis J Hornicek
Journal:  J Surg Oncol       Date:  2014-04-19       Impact factor: 3.454

3.  The effect of local recurrence on survival time in adult high-grade soft tissue sarcomas.

Authors:  L J Emrich; W Ruka; D L Driscoll; C P Karakousis
Journal:  J Clin Epidemiol       Date:  1989       Impact factor: 6.437

4.  The American Brachytherapy Society recommendations for brachytherapy of soft tissue sarcomas.

Authors:  S Nag; D Shasha; N Janjan; I Petersen; M Zaider
Journal:  Int J Radiat Oncol Biol Phys       Date:  2001-03-15       Impact factor: 7.038

Review 5.  Soft tissue sarcoma and radiation therapy advances, impact on toxicity.

Authors:  Nancy El-Bared; Philip Wong; Dian Wang
Journal:  Curr Treat Options Oncol       Date:  2015-05

6.  Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma.

Authors:  P W Pisters; L B Harrison; D H Leung; J M Woodruff; E S Casper; M F Brennan
Journal:  J Clin Oncol       Date:  1996-03       Impact factor: 44.544

7.  Local control comparison of adjuvant brachytherapy to intensity-modulated radiotherapy in primary high-grade sarcoma of the extremity.

Authors:  Kaled M Alektiar; Murray F Brennan; Samuel Singer
Journal:  Cancer       Date:  2011-01-24       Impact factor: 6.860

Review 8.  Opportunities for improving the therapeutic ratio for patients with sarcoma.

Authors:  Jay S Wunder; Torsten O Nielsen; Robert G Maki; Brian O'Sullivan; Benjamin A Alman
Journal:  Lancet Oncol       Date:  2007-06       Impact factor: 41.316

Review 9.  Proton beam therapy.

Authors:  W P Levin; H Kooy; J S Loeffler; T F DeLaney
Journal:  Br J Cancer       Date:  2005-10-17       Impact factor: 7.640

10.  Excellent local control with IOERT and postoperative EBRT in high grade extremity sarcoma: results from a subgroup analysis of a prospective trial.

Authors:  Falk Roeder; Burkhard Lehner; Thomas Schmitt; Bernd Kasper; Gerlinde Egerer; Oliver Sedlaczek; Carsten Grüllich; Gunhild Mechtersheimer; Patrick Wuchter; Frank W Hensley; Peter E Huber; Juergen Debus; Marc Bischof
Journal:  BMC Cancer       Date:  2014-05-20       Impact factor: 4.430

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  4 in total

1.  PLOD Family: A Novel Biomarker for Prognosis and Personalized Treatment in Soft Tissue Sarcoma.

Authors:  Siming Gong; Nikolas Schopow; Yingjuan Duan; Changwu Wu; Sonja Kallendrusch; Georg Osterhoff
Journal:  Genes (Basel)       Date:  2022-04-28       Impact factor: 4.141

2.  The Role of Radiotherapy in Soft Tissue Sarcoma on Extremities With Lymph Nodes Metastasis: An IPTW Propensity Score Analysis of the SEER Database.

Authors:  Xinzhu Qiu; Hongbo He; Hao Zeng; Xiaopeng Tong; Qing Liu
Journal:  Front Oncol       Date:  2021-10-21       Impact factor: 6.244

3.  Magnetic Resonance Imaging or Ultrasound in Localized Intermediate- or High-Risk Soft Tissue Tumors of the Extremities (MUSTT): Final Results of a Prospective Comparative Trial.

Authors:  Bianca Bignotti; Federica Rossi; Alessio Signori; Nicola Solari; Bruno Spina; Carlo Martinoli; Alberto Stefano Tagliafico
Journal:  Diagnostics (Basel)       Date:  2022-02-05

4.  CSPG4 expression in soft tissue sarcomas is associated with poor prognosis and low cytotoxic immune response.

Authors:  Laurys Boudin; A de Nonneville; Pascal Finetti; Léna Mescam; A Le Cesne; Antoine Italiano; Jean-Yves Blay; Daniel Birnbaum; Emilie Mamessier; François Bertucci
Journal:  J Transl Med       Date:  2022-10-11       Impact factor: 8.440

  4 in total

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