D L Dräger1, S Milerski2, K D Sievert2, O W Hakenberg2. 1. Klinik und Poliklinik für Urologie, Universitätsmedizin Rostock, Schillingallee 35, 18057, Rostock, Deutschland. desiree.draeger@med.uni-rostock.de. 2. Klinik und Poliklinik für Urologie, Universitätsmedizin Rostock, Schillingallee 35, 18057, Rostock, Deutschland.
Abstract
BACKGROUND: Psychological stress of patients with penile cancer arises from the cancer diagnosis itself and the treatment consequences. In addition, there is cancer-specific distress. There is the chance of cure in localized stages and in those with limited regional lymph node metastases but this requires surgery and often adjuvant chemotherapy. This systematic review gives a summary of the existing literature to date. MATERIALS AND METHODS: A critical database search using Medline was made in Ovid from 1946 to 2017, in the Cochrane Central Register of Controlled Trials (CENTRAL) and in the Web of Science from 1900 to 2017. This was complemented by a search of the World Health Organization's International Clinical Trials Registry Platform Search Portal and ClinicalTrials.gov. The reference lists of the included studies were manually searched for additional references. RESULTS: Selected studies (n = 10) addressed the psychosocial effects of penile cancer treatment on quality of life and sexual function. Due to the heterogeneity of the study designs only a narrative description of the results was possible. Defects or mutilation due to penile cancer cause psychological distress in a significant number of patients. Organ-sparing interventions have a positive impact on quality of life and sexual function. CONCLUSION: The external genitals are a focus of sexual identity. Mutilating treatment causes significant distress but organ-sparing treatment and reconstruction positively influence quality of life.
BACKGROUND: Psychological stress of patients with penile cancer arises from the cancer diagnosis itself and the treatment consequences. In addition, there is cancer-specific distress. There is the chance of cure in localized stages and in those with limited regional lymph node metastases but this requires surgery and often adjuvant chemotherapy. This systematic review gives a summary of the existing literature to date. MATERIALS AND METHODS: A critical database search using Medline was made in Ovid from 1946 to 2017, in the Cochrane Central Register of Controlled Trials (CENTRAL) and in the Web of Science from 1900 to 2017. This was complemented by a search of the World Health Organization's International Clinical Trials Registry Platform Search Portal and ClinicalTrials.gov. The reference lists of the included studies were manually searched for additional references. RESULTS: Selected studies (n = 10) addressed the psychosocial effects of penile cancer treatment on quality of life and sexual function. Due to the heterogeneity of the study designs only a narrative description of the results was possible. Defects or mutilation due to penile cancer cause psychological distress in a significant number of patients. Organ-sparing interventions have a positive impact on quality of life and sexual function. CONCLUSION: The external genitals are a focus of sexual identity. Mutilating treatment causes significant distress but organ-sparing treatment and reconstruction positively influence quality of life.
Entities:
Keywords:
Metastasis; Psycho-oncology; Psychological stress; Quality of life; Sexuality
Authors: V Ficarra; R Righetti; A D'Amico; S Pilloni; M Balzarro; D Schiavone; G Malossini; G Mobilio Journal: Urol Int Date: 2000 Impact factor: 2.089
Authors: Oliver W Hakenberg; Eva M Compérat; Suks Minhas; Andrea Necchi; Chris Protzel; Nick Watkin Journal: Eur Urol Date: 2014-11-01 Impact factor: 20.096
Authors: Zachary Klaassen; Rita P Jen; John M DiBianco; Lael Reinstatler; Qiang Li; Rabii Madi; Ronald W Lewis; Arthur M Smith; Durwood E Neal; Kelvin A Moses; Martha K Terris Journal: Cancer Date: 2015-02-17 Impact factor: 6.860
Authors: Jacobien M Kieffer; Rosa S Djajadiningrat; Erik A M van Muilekom; Niels M Graafland; Simon Horenblas; Neil K Aaronson Journal: J Urol Date: 2014-04-18 Impact factor: 7.450
Authors: Gaetano Gulino; Francesco Sasso; Giuseppe Palermo; Alfonso D'Onofrio; Marco Racioppi; Emilio Sacco; Francesco Pinto; Michele Antonucci; Alessandro D'Addessi; Pierfrancesco Bassi Journal: Indian J Urol Date: 2013-04
Authors: Vasileios I Sakalis; Riccardo Campi; Lenka Barreto; Herney Garcia Perdomo; Isabella Greco; Łukasz Zapala; Mithun Kailavasan; Tiago Antunes-Lopes; Jack David Marcus; Kenneth Manzie; John Osborne; Benjamin Ayres; Luc M F Moonen; Andrea Necchi; Juanita Crook; Pedro Oliveira; Lance C Pagliaro; Chris Protzel; Arie S Parnham; Maarten Albersen; Curtis A Pettaway; Philippe E Spiess; Scott T Tagawa; R Bryan Rumble; Oscar R Brouwer Journal: Eur Urol Open Sci Date: 2022-05-02
Authors: Steffen Lebentrau; Gamal Anton Wakileh; Martin Schostak; Hans-Peter Schmid; Rodrigo Suarez-Ibarrola; Axel S Merseburger; Georg C Hutterer; Ulrike H Necknig; Michael Rink; Martin Bögemann; Luis Alex Kluth; Armin Pycha; Maximilian Burger; Sabine D Brookman-May; Johannes Bründl; Matthias May Journal: Front Oncol Date: 2021-11-29 Impact factor: 6.244