| Literature DB >> 29475543 |
Eric Olinger1, Pascal Houillier2, Olivier Devuyst3.
Abstract
The claudins are the main proteins composing the tight junctions. The differential expression of claudin isoforms contributes to the specificity of paracellular transport pathways along the kidney tubule. Recent studies focusing on claudin-10 and claudin-16 support the longitudinal specialization of paracellular transport of cations within the thick ascending limb and demonstrate that complex tubular adaptations operate to buffer the consequences of chronic segmental lesions in the kidney.Entities:
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Year: 2018 PMID: 29475543 DOI: 10.1016/j.kint.2017.09.032
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612