Literature DB >> 29474916

The Unexpected Effects of the Combination of Antibiotics and Immunity.

Thomas P Burke1.   

Abstract

β-lactam antibiotics and immune enzymes, including lysozyme, kill bacteria by rupturing the cell wall. Curiously, their combination can select for viable, wall-less bacteria. Kawai and colleagues describe the molecular details regarding the emergence of these forms, illustrating a novel and potentially clinically relevant mechanism by which bacteria escape killing by antibiotics.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29474916     DOI: 10.1016/j.cell.2018.02.003

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  3 in total

1.  Proteomic Charting of Imipenem Adaptive Responses in a Highly Carbapenem Resistant Clinical Enterobacter roggenkampii Isolate.

Authors:  Suruchi Nepal; Sandra Maaß; Stefano Grasso; Francis M Cavallo; Jürgen Bartel; Dörte Becher; Erik Bathoorn; Jan Maarten van Dijl
Journal:  Antibiotics (Basel)       Date:  2021-04-28

Review 2.  Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic.

Authors:  Patrizia Ferraboschi; Samuele Ciceri; Paride Grisenti
Journal:  Antibiotics (Basel)       Date:  2021-12-14

3.  On-chip MIC by Combining Concentration Gradient Generator and Flanged Chamber Arrays.

Authors:  Xiao-Yan Zhang; Zhe-Yu Li; Kose Ueno; Hiroaki Misawa; Nan-Qi Ren; Kai Sun
Journal:  Micromachines (Basel)       Date:  2020-02-17       Impact factor: 2.891

  3 in total

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