Literature DB >> 29474694

A MONTE CARLO TOOL FOR MULTI-TARGET NANODOSIMETRY.

A Selva1,2, V Conte1, P Colautti1.   

Abstract

A Monte Carlo simulation tool has been developed, based on the physical models of the Geant4-DNA extension of Geant4, to study the ionisation pattern of charged particles in a multi-target environment. The tool allows to code easily the geometry to build a simulation with multiple targets, since several parameters can be changed interactively and independently via macro commands. In this work a set of nanometric target spheres is embedded in a cylindrical water phantom 20 nm in height and 40 nm in diameter. The targets are randomly distributed in such a way that they do not overlap and are contained within a smaller cylindrical volume 20 nm in diameter and height. The water phantom is irradiated by ions which are shot parallel to the central axis and randomly distributed over the cross section of the inner cylinder. Two different types of simulations are performed. In one, the penumbra of secondary electrons is fully simulated, in the other the transport of secondary electrons is carried out only if they are produced inside one of the targets, and the electron track is terminated when it leaves the sphere of production. First results are presented and discussed.

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Year:  2018        PMID: 29474694     DOI: 10.1093/rpd/ncy027

Source DB:  PubMed          Journal:  Radiat Prot Dosimetry        ISSN: 0144-8420            Impact factor:   0.972


  2 in total

Review 1.  Applications of nanodosimetry in particle therapy planning and beyond.

Authors:  Antoni Rucinski; Anna Biernacka; Reinhard Schulte
Journal:  Phys Med Biol       Date:  2021-12-10       Impact factor: 3.609

2.  Investigation into the foundations of the track-event theory of cell survival and the radiation action model based on nanodosimetry.

Authors:  Sonwabile Arthur Ngcezu; Hans Rabus
Journal:  Radiat Environ Biophys       Date:  2021-08-24       Impact factor: 1.925

  2 in total

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