Literature DB >> 29474257

Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children.

Mark P Nicol1, Lesley Workman2, Margaretha Prins2, Lindy Bateman2, Yonas Ghebrekristos1, Silindile Mbhele1, Claudia M Denkinger3, Heather J Zar2.   

Abstract

We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same specimen. Of those children with microbiologically confirmed tuberculosis (positive Xpert, Ultra or culture), Xpert detected 63.2%, Ultra 73.7% and culture 82.9%.

Entities:  

Mesh:

Year:  2018        PMID: 29474257     DOI: 10.1097/INF.0000000000001960

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  35 in total

1.  Evaluation of the Xpert MTB/RIF Ultra Assay for Direct Detection of Mycobacterium tuberculosis Complex in Smear-Negative Extrapulmonary Samples.

Authors:  Daniel Perez-Risco; David Rodriguez-Temporal; Ivan Valledor-Sanchez; Fernando Alcaide
Journal:  J Clin Microbiol       Date:  2018-08-27       Impact factor: 5.948

2.  Xpert MTB/RIF Ultra for Detection of Mycobacterium tuberculosis in Cerebrospinal Fluid.

Authors:  Jerome H Chin; Abdu K Musubire; Nicole Morgan; Jacob Pellinen; Scott Grossman; Jaydeep M Bhatt; Vincent Wadda; Willy Ssengooba
Journal:  J Clin Microbiol       Date:  2019-05-24       Impact factor: 5.948

3.  Xpert MTB/RIF diagnosis of childhood tuberculosis from sputum and stool samples in a high TB-HIV-prevalent setting.

Authors:  Patrick Orikiriza; Margaret Nansumba; Dan Nyehangane; Mathieu Bastard; Ivan Taremwa Mugisha; Denis Nansera; Juliet Mwanga-Amumpaire; Yap Boum; Elias Kumbakumba; Maryline Bonnet
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2018-05-08       Impact factor: 3.267

4.  Strengthening Diagnosis of Pulmonary Tuberculosis in Children: The Role of Xpert MTB/RIF Ultra.

Authors:  Heather J Zar; Mark P Nicol
Journal:  Pediatrics       Date:  2019-11       Impact factor: 7.124

Review 5.  Strategies for advanced personalized tuberculosis diagnosis: Current technologies and clinical approaches.

Authors:  Xuerong Chen; Tony Y Hu
Journal:  Precis Clin Med       Date:  2021-01-18

6.  Evaluating the efficacy of stool sample on Xpert MTB/RIF Ultra and its comparison with other sample types by meta-analysis for TB diagnostics.

Authors:  Vishal Sharma; Anoop Singh; Mohita Gaur; Deepti Rawat; Anjali Yadav; Chanchal Kumar; Mandira Varma-Basil; Sheelu Lohiya; Vishal Khanna; Ashwani Khanna; Anil Chaudhry; Yogendra Singh; Richa Misra
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2022-05-04       Impact factor: 3.267

7.  Tuberculosis Diagnosis in Children Using Xpert Ultra on Different Respiratory Specimens.

Authors:  Heather J Zar; Lesley J Workman; Margaretha Prins; Linda J Bateman; Slindile P Mbhele; Cynthia B Whitman; Claudia M Denkinger; Mark P Nicol
Journal:  Am J Respir Crit Care Med       Date:  2019-12-15       Impact factor: 21.405

8.  Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms.

Authors:  Adrienne E Shapiro; Jennifer M Ross; Mandy Yao; Ian Schiller; Mikashmi Kohli; Nandini Dendukuri; Karen R Steingart; David J Horne
Journal:  Cochrane Database Syst Rev       Date:  2021-03-23

9.  A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda.

Authors:  Devan Jaganath; Peter Wambi; Tania F Reza; Jascent Nakafeero; Ernest O Aben; Emma Kiconco; Gertrude Nannyonga; Moses Nsereko; Moorine P Sekadde; Mary Mudiope; Midori Kato-Maeda; Jeffrey Starke; Alfred Andama; Swomitra Mohanty; Eric Wobudeya; Adithya Cattamanchi
Journal:  J Pediatric Infect Dis Soc       Date:  2021-05-28       Impact factor: 3.164

Review 10.  Adolescent tuberculosis.

Authors:  Kathryn J Snow; Andrea T Cruz; James A Seddon; Rashida A Ferrand; Silvia S Chiang; Jennifer A Hughes; Beate Kampmann; Steve M Graham; Peter J Dodd; Rein M Houben; Justin T Denholm; Susan M Sawyer; Katharina Kranzer
Journal:  Lancet Child Adolesc Health       Date:  2019-11-18
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