Xiaowen Wang1, Guangping Guo2, Xiumin Liang3, Ling Zhou2, Jiarui Zheng2, Shaoqin Li4, Hongzhuan Luo5, Yuyan Yang6, Liyuan Yang7, Ting Tan8, Jun Yu8, Lin Lu9. 1. Yunnan Centers for Disease Control and Prevention, Kunming, Yunnan, China; Department of Public Health, Kunming Medical University, Kunming, Yunnan, China. 2. Yunnan Maternal and Child Health Care hospital, Kunming, Yunnan, China. 3. Yiliang County Centers for Disease Control and Prevention, Zhaotong, Yunnan, China. 4. Longling County Centers for Disease Control and Prevention, Baoshan, Yunnan, China. 5. Fengqing County Centers for Disease Control and Prevention, Lincang, Yunnan, China. 6. Longchuan County Maternal and Child Health Care hospital, Dehong, Yunnan, China. 7. Longling County Maternal and Child Health Care hospital, Baoshan, Yunnan, China. 8. Department of Public Health, Kunming Medical University, Kunming, Yunnan, China. 9. Department of Public Health, Kunming Medical University, Kunming, Yunnan, China; Health and Family Planning Commission of Yunnan Province, Kunming, Yunnan, China. Electronic address: Lulin62_wjw@163.com.
Abstract
BACKGROUND: Health utility (HU) is essential to understanding the effects of HIV infection as a chronic disease. No HU data on pregnant women living with human immunodeficiency virus (HIV) in Yunnan Province are available. This study aims to construct a database on HU and explore factors associated with HU by pregnant women living with HIV/acquired immunodeficiency syndrome (AIDS) who were enrolled in the Prevention of mother-to-child transmission of HIV (PMTCT) programs in Yunnan Province. METHODS: A cross-sectional study was conducted in Yunnan Province on pregnant women living with HIV who were selected by convenience sampling. Sociodemographic, HIV-related, social support, and HU data were collected through face-to-face interviews. The European quality of life five-dimensional three-level (EQ-5D-3L) questionnaire and the social support rate scale (SSRS) were applied. RESULTS: One hundred and one pregnant women (mean age of 30.4 ± 5.1 years) participated in the survey. The mean EQ-5D index score and the EQ visual analogue scale (EQ-VAS) score of participants were 0.77 (95% confidence interval [CI] 0.74-0.79) and 75.77 (95% CI 75.00-80.00), respectively. The effect of social support on HU was maintained significant difference even after adjusting for such factors as education level, household income per year, and HIV disclosure, demonstrating a significant difference within EQ-5D index scores and EQ-VAS scores. CONCLUSIONS: Pregnant women living with HIV/AIDS who were enrolled in PMTCT programs reported the same level of HU as other patients living with HIV/AIDS. Integrating measurements of HU by using the EQ-5D-3L questionnaire could be helpful for economic evaluation of the PMTCT program. This study also suggests a potential benefit of appropriate social support.
BACKGROUND: Health utility (HU) is essential to understanding the effects of HIV infection as a chronic disease. No HU data on pregnant women living with human immunodeficiency virus (HIV) in Yunnan Province are available. This study aims to construct a database on HU and explore factors associated with HU by pregnant women living with HIV/acquired immunodeficiency syndrome (AIDS) who were enrolled in the Prevention of mother-to-child transmission of HIV (PMTCT) programs in Yunnan Province. METHODS: A cross-sectional study was conducted in Yunnan Province on pregnant women living with HIV who were selected by convenience sampling. Sociodemographic, HIV-related, social support, and HU data were collected through face-to-face interviews. The European quality of life five-dimensional three-level (EQ-5D-3L) questionnaire and the social support rate scale (SSRS) were applied. RESULTS: One hundred and one pregnant women (mean age of 30.4 ± 5.1 years) participated in the survey. The mean EQ-5D index score and the EQ visual analogue scale (EQ-VAS) score of participants were 0.77 (95% confidence interval [CI] 0.74-0.79) and 75.77 (95% CI 75.00-80.00), respectively. The effect of social support on HU was maintained significant difference even after adjusting for such factors as education level, household income per year, and HIV disclosure, demonstrating a significant difference within EQ-5D index scores and EQ-VAS scores. CONCLUSIONS: Pregnant women living with HIV/AIDS who were enrolled in PMTCT programs reported the same level of HU as other patients living with HIV/AIDS. Integrating measurements of HU by using the EQ-5D-3L questionnaire could be helpful for economic evaluation of the PMTCT program. This study also suggests a potential benefit of appropriate social support.