Literature DB >> 29473581

Treatment considerations of cervical spondylotic myelopathy.

Ehab Shiban1, Bernhard Meyer1.   

Abstract

Cervical spondylotic myelopathy (CSM) is the leading cause of myelopathy in patients over age 50 years. Despite advances, CSM remains a clinical diagnosis and its natural history remains unclear. The treatment of CSM is controversial, especially in patients with mild or moderate clinical disease without rapid progression of symptoms. Herein, we begin with a clinical vignette followed by a brief description of the clinical problems. We discuss evaluation, treatment, and recommendations for the treatment of CSM. Emphasis is drawn to areas of uncertainty and present level of evidence for the treatment modalities of CSM.

Entities:  

Year:  2014        PMID: 29473581      PMCID: PMC5764527          DOI: 10.1212/CPJ.0000000000000050

Source DB:  PubMed          Journal:  Neurol Clin Pract        ISSN: 2163-0402


  20 in total

1.  The clinical manifestations of spondylochondrosis (spondylosis) of the cervical spine.

Authors:  J G ARNOLD
Journal:  Ann Surg       Date:  1955-06       Impact factor: 12.969

2.  Cervical myelopathy: a complication of cervical spondylosis.

Authors:  E CLARKE; P K ROBINSON
Journal:  Brain       Date:  1956-09       Impact factor: 13.501

3.  Human neuropathological and animal model evidence supporting a role for Fas-mediated apoptosis and inflammation in cervical spondylotic myelopathy.

Authors:  Wen Ru Yu; Tianyi Liu; Tim-Rasmus Kiehl; Michael G Fehlings
Journal:  Brain       Date:  2011-04-13       Impact factor: 13.501

Review 4.  Cervical spondylotic myelopathy: a common cause of spinal cord dysfunction in older persons.

Authors:  W F Young
Journal:  Am Fam Physician       Date:  2000-09-01       Impact factor: 3.292

5.  Tight squeeze, slow burn: inflammation and the aetiology of cervical myelopathy.

Authors:  Michael S Beattie; Geoffrey T Manley
Journal:  Brain       Date:  2011-05       Impact factor: 13.501

Review 6.  The pathophysiology of cervical spondylosis and myelopathy.

Authors:  H H Bohlman; S E Emery
Journal:  Spine (Phila Pa 1976)       Date:  1988-07       Impact factor: 3.468

Review 7.  Biomechanics of nonacute cervical spinal cord trauma.

Authors:  M Panjabi; A White
Journal:  Spine (Phila Pa 1976)       Date:  1988-07       Impact factor: 3.468

8.  Biomechanical aspects of spondylotic myelopathy.

Authors:  L Penning; P van der Zwaag
Journal:  Acta Radiol Diagn (Stockh)       Date:  1966

Review 9.  Cervical spondylotic myelopathy: the clinical phenomenon and the current pathobiology of an increasingly prevalent and devastating disorder.

Authors:  Sukhvinder Kalsi-Ryan; Spyridon K Karadimas; Michael G Fehlings
Journal:  Neuroscientist       Date:  2012-11-30       Impact factor: 7.519

Review 10.  A review of the pathophysiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury.

Authors:  M G Fehlings; G Skaf
Journal:  Spine (Phila Pa 1976)       Date:  1998-12-15       Impact factor: 3.468

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  1 in total

Review 1.  Reported Outcome Measures in Degenerative Cervical Myelopathy: A Systematic Review.

Authors:  Benjamin M Davies; Maire McHugh; Ali Elgheriani; Angelos G Kolias; Lindsay A Tetreault; Peter J A Hutchinson; Michael G Fehlings; Mark R N Kotter
Journal:  PLoS One       Date:  2016-08-02       Impact factor: 3.240

  1 in total

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