| Literature DB >> 29473160 |
Shuai Jiang1,2, Tian Li3, Zhi Yang3, Wei Hu3, Yang Yang1,3.
Abstract
Neoplasms constituted an enormous burden and contributed to an estimated 8.2 million deaths in 2012 worldwide. FOXO1 (forkhead box O1), a member of the forkhead box (FOX) family, is a transcriptional factor involved in diverse cellular functions. Herein, we concentrate on recent studies of the antineoplastic roles of FOXO1 in neoplasms. This article may serve as a guide for future research and identify FOXO1 as a potent therapeutic target in neoplasms.Entities:
Keywords: Forkhead box O1; apoptosis; microRNA; neoplasm; phosphorylation; proliferation
Year: 2018 PMID: 29473160 DOI: 10.1002/ijc.31338
Source DB: PubMed Journal: Int J Cancer ISSN: 0020-7136 Impact factor: 7.396