PURPOSE: To propose a geometrical margin for definition of the vaginal cuff PTV using only CT images of the full bladder (CTfull) in postoperative cervical cancer patients. METHODS: Twenty-nine operated cervical cancer patients underwent volumetric arc therapy with a bladder filling protocol. This study assessed bladder filling using a portable bladder scanner and cone-beam computed tomography (CBCT) during the entire treatment period. The measured bladder volumes with a BladderScan® were compared with the delineated volume on CBCT. Titanium clips in the vaginal cuff were analysed to assess geometrical uncertainty and the influence of rectal and bladder volume changes. RESULTS: BladderScan® showed good agreement with the delineated volume (R = 0.80). The volume changes in the bladder have a greater influence on the clip displacements than in the rectum. The 95th percentile of uncertainty of the clips in reference to CTfull in the right-left (RL), the superoinferior (SI), and the anteroposterior (AP) was 0.32, 0.65, and 1.15 cm, respectively. From this result and intra-fractional movements of the vaginal cuff reported by Haripotepornkul, a new geometrical margin was proposed for definition of the vaginal cuff planning target volume (PTV): 0.5, 0.9, and 1.4 cm in the RL, SI, and AP directions, respectively. CONCLUSIONS: A new geometrical margin was proposed for definition of the vaginal cuff PTV based on CTfull, which will be needless of empty bladder at the planning CT scan. This method allows patients to reduce the burden and efficient routine CT scans can be improved.
PURPOSE: To propose a geometrical margin for definition of the vaginal cuff PTV using only CT images of the full bladder (CTfull) in postoperative cervical cancerpatients. METHODS: Twenty-nine operated cervical cancerpatients underwent volumetric arc therapy with a bladder filling protocol. This study assessed bladder filling using a portable bladder scanner and cone-beam computed tomography (CBCT) during the entire treatment period. The measured bladder volumes with a BladderScan® were compared with the delineated volume on CBCT. Titanium clips in the vaginal cuff were analysed to assess geometrical uncertainty and the influence of rectal and bladder volume changes. RESULTS: BladderScan® showed good agreement with the delineated volume (R = 0.80). The volume changes in the bladder have a greater influence on the clip displacements than in the rectum. The 95th percentile of uncertainty of the clips in reference to CTfull in the right-left (RL), the superoinferior (SI), and the anteroposterior (AP) was 0.32, 0.65, and 1.15 cm, respectively. From this result and intra-fractional movements of the vaginal cuff reported by Haripotepornkul, a new geometrical margin was proposed for definition of the vaginal cuff planning target volume (PTV): 0.5, 0.9, and 1.4 cm in the RL, SI, and AP directions, respectively. CONCLUSIONS: A new geometrical margin was proposed for definition of the vaginal cuff PTV based on CTfull, which will be needless of empty bladder at the planning CT scan. This method allows patients to reduce the burden and efficient routine CT scans can be improved.
Authors: Ingrid White; Dualta McQuaid; Helen McNair; Alex Dunlop; Steven Court; Naomi Hopkins; Karen Thomas; David Dearnaley; Shree Bhide; Susan Lalondrelle Journal: Phys Imaging Radiat Oncol Date: 2019-04-05