| Literature DB >> 29471011 |
Elizabeth Buckingham-Jeffery1, Valerie Isham2, Thomas House3.
Abstract
We present a flexible framework for deriving and quantifying the accuracy of Gaussian process approximations to non-linear stochastic individual-based models of epidemics. We develop this for the SIR and SEIR models, and we show how it can be used to perform quick maximum likelihood inference for the underlying parameters given population estimates of the number of infecteds or cases at given time points. We also show how the unobserved processes can be inferred at the same time as the underlying parameters.Entities:
Keywords: MLE; SEIR; SIR; Stochastic Taylor expansion
Mesh:
Year: 2018 PMID: 29471011 DOI: 10.1016/j.mbs.2018.02.003
Source DB: PubMed Journal: Math Biosci ISSN: 0025-5564 Impact factor: 2.144