Literature DB >> 29470044

Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications.

Aaqil Rifai, Nhiem Tran, Desmond W Lau, Aaron Elbourne, Hualin Zhan1, Alastair D Stacey1, Edwin L H Mayes2, Avik Sarker, Elena P Ivanova3, Russell J Crawford, Phong A Tran4, Brant C Gibson, Andrew D Greentree, Elena Pirogova, Kate Fox.   

Abstract

Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for "just in time" implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.

Entities:  

Keywords:  TI6Al4V; additive manufacturing; adhesive coatings; biomaterials; diamond

Mesh:

Substances:

Year:  2018        PMID: 29470044     DOI: 10.1021/acsami.7b18596

Source DB:  PubMed          Journal:  ACS Appl Mater Interfaces        ISSN: 1944-8244            Impact factor:   9.229


  6 in total

Review 1.  Additive manufacturing of bone scaffolds.

Authors:  Youwen Yang; Guoyong Wang; Huixin Liang; Chengde Gao; Shuping Peng; Lida Shen; Cijun Shuai
Journal:  Int J Bioprint       Date:  2018-12-12

2.  Recent advances in biomaterials for 3D scaffolds: A review.

Authors:  Maria P Nikolova; Murthy S Chavali
Journal:  Bioact Mater       Date:  2019-10-25

Review 3.  Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances.

Authors:  Jingyuan Xu; Jiawen Zhang; Yangfan Shi; Jincheng Tang; Danni Huang; Ming Yan; Matthew S Dargusch
Journal:  Materials (Basel)       Date:  2022-02-25       Impact factor: 3.623

Review 4.  Advanced Surface Modification for 3D-Printed Titanium Alloy Implant Interface Functionalization.

Authors:  Xiao Sheng; Ao Wang; Zhonghan Wang; He Liu; Jincheng Wang; Chen Li
Journal:  Front Bioeng Biotechnol       Date:  2022-03-01

5.  Zein regulating apatite mineralization, degradability, in vitro cells responses and in vivo osteogenesis of 3D-printed scaffold of n-MS/ZN/PCL ternary composite.

Authors:  Jiangying Ru; Qiang Wei; Lianqing Yang; Jing Qin; Liangchen Tang; Jie Wei; Lieping Guo; Yunfei Niu
Journal:  RSC Adv       Date:  2018-05-22       Impact factor: 3.361

6.  Polycrystalline Diamond Coating on Orthopedic Implants: Realization and Role of Surface Topology and Chemistry in Adsorption of Proteins and Cell Proliferation.

Authors:  Justas Zalieckas; Ivan R Mondragon; Paulius Pobedinskas; Arne S Kristoffersen; Samih Mohamed-Ahmed; Cecilie Gjerde; Paul J Høl; Geir Hallan; Ove N Furnes; Mihaela Roxana Cimpan; Ken Haenen; Bodil Holst; Martin M Greve
Journal:  ACS Appl Mater Interfaces       Date:  2022-09-22       Impact factor: 10.383

  6 in total

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