Literature DB >> 29464377

Is oral feeding compatible with an unresponsive wakefulness syndrome?

Evelyne Mélotte1,2, Audrey Maudoux3,4, Sabrina Delhalle4, Charlotte Martial3, Georgios Antonopoulos3, Stephen Karl Larroque3, Sarah Wannez3, Marie-Elisabeth Faymonville5, Jean-François Kaux6, Steven Laureys3, Olivia Gosseries3, Audrey Vanhaudenhuyse3,5.   

Abstract

OBJECTIVE: The aim of the study is to explore the possibility of oral feeding in unresponsive wakefulness syndrome/vegetative state (UWS/VS) patients.
METHOD: We reviewed the clinical information of 68 UWS/VS patients (mean age 45 ± 11; range 16-79 years) searching for mention of oral feeding. UWS/VS diagnosis was made after repeated behavioural assessments using the Coma Recovery Scale-Revised. Patients also had complementary neuroimaging evaluations (positron emission tomography, functional magnetic resonance imaging and electroencephalography and diffusion tensor imaging).
RESULTS: Out of the 68 UWS/VS patients, only two could resume oral feeding (3%). The first patient had oral feeding (only liquid and semi liquid) in addition to gastrostomy feeding and the second one could achieve full oral feeding (liquid and mixed solid food). Clinical assessments concluded that they fulfilled the criteria for a diagnosis of UWS/VS. Results from neuroimaging and neurophysiology were typical for the first patient with regard to the diagnosis of UWS/VS but atypical for the second patient.
CONCLUSION: Oral feeding that implies a full and complex oral phase could probably be considered as a sign of consciousness. However, we actually do not know which components are necessary to consider the swallowing conscious as compared to reflex. We also discussed the importance of swallowing assessment and management in all patients with altered state of consciousness.

Entities:  

Keywords:  Consciousness; Dysphagia; Oral-feeding; Swallowing; Unresponsive wakefulness syndrome

Mesh:

Substances:

Year:  2018        PMID: 29464377     DOI: 10.1007/s00415-018-8794-y

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  40 in total

1.  The functional neuroanatomy of voluntary swallowing.

Authors:  D H Zald; J V Pardo
Journal:  Ann Neurol       Date:  1999-09       Impact factor: 10.422

Review 2.  From unresponsive wakefulness to minimally conscious PLUS and functional locked-in syndromes: recent advances in our understanding of disorders of consciousness.

Authors:  Marie-Aurélie Bruno; Audrey Vanhaudenhuyse; Aurore Thibaut; Gustave Moonen; Steven Laureys
Journal:  J Neurol       Date:  2011-06-16       Impact factor: 4.849

3.  Persons with disorders of consciousness: are oral feedings safe/effective?

Authors:  Susan L Brady; Meghan Darragh; Nelson G Escobar; Kara O'Neil; Theresa L B Pape; Noel Rao
Journal:  Brain Inj       Date:  2006-12       Impact factor: 2.311

4.  Persistent vegetative state: report of the American Neurological Association Committee on Ethical Affairs. ANA Committee on Ethical Affairs.

Authors: 
Journal:  Ann Neurol       Date:  1993-04       Impact factor: 10.422

5.  Fetal deglutition: a study of the anencephalic fetus.

Authors:  D Peleg; J A Goldman
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  1978-06       Impact factor: 2.435

6.  Functional neuroimaging in the vegetative state.

Authors:  Steven Laureys
Journal:  NeuroRehabilitation       Date:  2004       Impact factor: 2.138

7.  Sedation of Patients With Disorders of Consciousness During Neuroimaging: Effects on Resting State Functional Brain Connectivity.

Authors:  Muriëlle Kirsch; Pieter Guldenmund; Mohamed Ali Bahri; Athena Demertzi; Katherine Baquero; Lizette Heine; Vanessa Charland-Verville; Audrey Vanhaudenhuyse; Marie-Aurélie Bruno; Olivia Gosseries; Carol Di Perri; Erik Ziegler; Jean-François Brichant; Andrea Soddu; Vincent Bonhomme; Steven Laureys
Journal:  Anesth Analg       Date:  2017-02       Impact factor: 5.108

8.  Swallowing Disorders in Severe Brain Injury in the Arousal Phase.

Authors:  A Bremare; A Rapin; B Veber; F Beuret-Blanquart; E Verin
Journal:  Dysphagia       Date:  2016-04-18       Impact factor: 3.438

9.  Prevalence and associated factors of pneumonia in patients with vegetative state in Taiwan.

Authors:  Li-Chan Lin; Pei-Chi Hsieh; Shiao-Chi Wu
Journal:  J Clin Nurs       Date:  2007-04-05       Impact factor: 3.036

10.  Functional MRI Motor Imagery Tasks to Detect Command Following in Traumatic Disorders of Consciousness.

Authors:  Yelena G Bodien; Joseph T Giacino; Brian L Edlow
Journal:  Front Neurol       Date:  2017-12-18       Impact factor: 4.003

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  6 in total

1.  Nursing, Caregiving and Psychological support in Chronic Disorders of Consciousness: a scoping review.

Authors:  Loredana Raciti; Francesco Corallo; Alfredo Manuli; Rocco Salvatore Calabrò
Journal:  Acta Biomed       Date:  2021-03-31

Review 2.  Links Between Swallowing and Consciousness: A Narrative Review.

Authors:  Evelyne Mélotte; Audrey Maudoux; Rajanikant Panda; Jean-François Kaux; Aude Lagier; Roxanne Herr; Marion Belorgeot; Steven Laureys; Olivia Gosseries
Journal:  Dysphagia       Date:  2022-06-30       Impact factor: 3.438

Review 3.  Understanding, detecting, and stimulating consciousness recovery in the ICU.

Authors:  Daniel Kondziella; Moshgan Amiri; Marwan H Othman; Elisabeth Waldemar Jakobsen; Tejs Jansen; Kirsten Møller
Journal:  Acta Neurochir (Wien)       Date:  2022-10-15       Impact factor: 2.816

Review 4.  Neurogenic Dysphagia and Nutrition in Disorder of Consciousness: An Overview with Practical Advices on an "Old" but Still Actual Clinical Problem.

Authors:  Loredana Raciti; Gianfranco Raciti; Grazia Pulejo; Valeria Conti-Nibali; Rocco Salvatore Calabrò
Journal:  Medicines (Basel)       Date:  2022-02-21

5.  SWALLOWING ACTIVATION USING SENSORY STIMULATION IN PATIENTS WITH SEVERE DISORDERS OF CONSCIOUSNESS.

Authors:  Grégoire Prum; Rémi Mallart; Margaux Beatrix; Eric Verin
Journal:  J Rehabil Med Clin Commun       Date:  2022-06-13

6.  A Precision Medicine Framework for Classifying Patients with Disorders of Consciousness: Advanced Classification of Consciousness Endotypes (ACCESS).

Authors:  Daniel Kondziella; David K Menon; Raimund Helbok; Lionel Naccache; Marwan H Othman; Verena Rass; Benjamin Rohaut; Michael N Diringer; Robert D Stevens
Journal:  Neurocrit Care       Date:  2021-07-08       Impact factor: 3.210

  6 in total

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