Literature DB >> 29464306

[Surgical aspects of neuroendocrine tumors of the small intestine].

F Weber1, H Dralle2.   

Abstract

Neuroendocrine tumors of the small intestines are a rare disease with an incidence of 1 per 100,000 of the population; however, they account for over 20% of all neuroendocrine tumors and are the most common malignancy of the small intestines. Diagnosis is often made at a late stage of the disease, as the clinical symptoms are unspecific. Approximately one third of all patients show hepatic metastases at the time of diagnosis. There is no correlation between tumor size and tumor stage. Even small tumors <10 mm harbor the risk for lymphatic and distant metastases so that the extent of surgery is not determined by the size of the primary tumor. The intestinal-sparing resection with systematic lymphadenectomy along the superior mesenteric artery and removal of the retropancreatic lymph nodes is recommended even in localized stages of the disease.

Entities:  

Keywords:  Desmoplasia; Localized disease; Lymphadenectomy; Mesenterial fibrosis; Skip metastases

Mesh:

Year:  2018        PMID: 29464306     DOI: 10.1007/s00104-018-0607-4

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  20 in total

1.  Resection of at-risk mesenteric lymph nodes is associated with improved survival in patients with small bowel neuroendocrine tumors.

Authors:  Christine S Landry; Heather Y Lin; Alexandria Phan; Chusilp Charnsangavej; Eddie K Abdalla; Thomas Aloia; J Nicolas Vauthey; Matthew H G Katz; James C Yao; Jason B Fleming
Journal:  World J Surg       Date:  2013-07       Impact factor: 3.352

2.  Should mesenteric tumor deposits be included in staging of well-differentiated small intestine neuroendocrine tumors?

Authors:  Raul S Gonzalez; Eric H Liu; JoAnn R Alvarez; Gregory D Ayers; M Kay Washington; Chanjuan Shi
Journal:  Mod Pathol       Date:  2014-01-24       Impact factor: 7.842

Review 3.  Systematic review of resection of primary midgut carcinoid tumour in patients with unresectable liver metastases.

Authors:  G Capurso; M Rinzivillo; R Bettini; L Boninsegna; G Delle Fave; M Falconi
Journal:  Br J Surg       Date:  2012-09-13       Impact factor: 6.939

4.  Mesenteric fibrosis and palliative surgery in small intestinal neuroendocrine tumours.

Authors:  Anela Blažević; Wouter T Zandee; Gaston J H Franssen; Johannes Hofland; Marie-Louise F van Velthuysen; Leo J Hofland; Richard A Feelders; Wouter W de Herder
Journal:  Endocr Relat Cancer       Date:  2017-12-18       Impact factor: 5.678

Review 5.  Small intestinal neuroendocrine tumours and fibrosis: an entangled conundrum.

Authors:  Anela Blažević; Johannes Hofland; Leo J Hofland; Richard A Feelders; Wouter W de Herder
Journal:  Endocr Relat Cancer       Date:  2017-12-12       Impact factor: 5.678

Review 6.  [Neuroendocrine neoplasms of the distal jejunum and ileum].

Authors:  M Anlauf; B Sipos; I Boeck; S E Baldus; S Heikaus; M Krausch; W T Knoefel; N Begum; P Goretzki; M Schott; C J Auernhammer; B Cremer; A Rinke; S Ezziddin; C Fottner; G Pöpperl; H Lahner; D Hörsch; H E Gabbert; P Komminoth; A Perren; G Klöppel; B Wiedenmann; M Pavel; U Pape
Journal:  Pathologe       Date:  2014-05       Impact factor: 1.011

7.  Operative resection of primary carcinoid neoplasms in patients with liver metastases yields significantly better survival.

Authors:  Babak Givi; Suellen J Pommier; Alivia K Thompson; Brian S Diggs; Rodney F Pommier
Journal:  Surgery       Date:  2006-12       Impact factor: 3.982

8.  Prophylactic cholecystectomy in midgut carcinoid patients.

Authors:  Olov Norlén; Ola Hessman; Peter Stålberg; Göran Akerström; Per Hellman
Journal:  World J Surg       Date:  2010-06       Impact factor: 3.352

9.  Small bowel neuroendocrine tumors: A critical analysis of diagnostic work-up and operative approach.

Authors:  Cecilia G Ethun; Lauren M Postlewait; Gillian G Baptiste; Mia R McInnis; Kenneth Cardona; Maria C Russell; David A Kooby; Charles A Staley; Shishir K Maithel
Journal:  J Surg Oncol       Date:  2016-08-11       Impact factor: 3.454

10.  Surgical Treatment of NEN of Small Bowel: A Retrospective Analysis.

Authors:  F M Watzka; C Fottner; M Miederer; M M Weber; A Schad; H Lang; T J Musholt
Journal:  World J Surg       Date:  2016-03       Impact factor: 3.352

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