Literature DB >> 29462104

High Incidence of Tuberculosis Infection in HIV-exposed Children Exiting an Isoniazid Preventive Therapy Trial.

Lisa M Cranmer1, Heather R Draper2, Anna M Mandalakas3, Soyeon Kim4, George McSherry5, Emma Krezinski2, Joan Coetzee2, Charles Mitchell6, Sharon Nachman7, Mercia van der Linde2, Mark F Cotton8, Anneke C Hesseling2.   

Abstract

Young HIV-exposed children are at high risk for TB infection. We performed QuantiFERON-TB Gold among HIV-exposed children in South Africa at enrolment and 1-year follow-up. The incidence of TB infection was high for HIV+ (11 cases per 100 child-years) and HIV-exposed uninfected children (15 cases per 100 child-years). QuantiFERON-TB Gold may identify HIV-exposed children at risk for TB disease progression.

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Year:  2018        PMID： 29462104      PMCID： PMC6095832          DOI： 10.1097/INF.0000000000001946

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  8 in total

1.  Source case identification in HIV-exposed infants and tuberculosis diagnosis in an isoniazid prevention study.

Authors:  E R Maritz; G Montepiedra; L Liu; C D Mitchell; S A Madhi; R Bobat; A Violari; A Ogwu; A C Hesseling; M F Cotton
Journal:  Int J Tuberc Lung Dis       Date:  2016-08       Impact factor: 2.373

2.  Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study.

Authors:  Jason R Andrews; Elisa Nemes; Michele Tameris; Bernard S Landry; Hassan Mahomed; J Bruce McClain; Helen A Fletcher; Willem A Hanekom; Robin Wood; Helen McShane; Thomas J Scriba; Mark Hatherill
Journal:  Lancet Respir Med       Date:  2017-02-16       Impact factor: 30.700

3.  Primary isoniazid prophylaxis against tuberculosis in HIV-exposed children.

Authors:  Shabir A Madhi; Sharon Nachman; Avy Violari; Soyeon Kim; Mark F Cotton; Raziya Bobat; Patrick Jean-Philippe; George McSherry; Charles Mitchell
Journal:  N Engl J Med       Date:  2011-07-07       Impact factor: 91.245

Review 4.  Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis.

Authors:  A M Mandalakas; A K Detjen; A C Hesseling; A Benedetti; D Menzies
Journal:  Int J Tuberc Lung Dis       Date:  2011-08       Impact factor: 2.373

5.  Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection.

Authors:  A M Mandalakas; H L Kirchner; C Lombard; G Walzl; H M S Grewal; R P Gie; A C Hesseling
Journal:  Int J Tuberc Lung Dis       Date:  2012-06-11       Impact factor: 2.373

6.  High incidence of tuberculosis among HIV-infected infants: evidence from a South African population-based study highlights the need for improved tuberculosis control strategies.

Authors:  A C Hesseling; M F Cotton; T Jennings; A Whitelaw; L F Johnson; B Eley; P Roux; P Godfrey-Faussett; H S Schaaf
Journal:  Clin Infect Dis       Date:  2009-01-01       Impact factor: 9.079

7.  Tuberculosis Infection in Early Childhood and the Association with HIV-exposure in HIV-uninfected Children in Rural Uganda.

Authors:  Carina Marquez; Gabriel Chamie; Jane Achan; Anne F Luetkemeyer; Mary Kyohere; Jaffer Okiring; Grant Dorsey; Moses R Kamya; Edwin D Charlebois; Diane V Havlir
Journal:  Pediatr Infect Dis J       Date:  2016-05       Impact factor: 2.129

8.  High prevalence of tuberculosis infection in HIV-1 exposed Kenyan infants.

Authors:  Lisa M Cranmer; Mercy Kanyugo; Sasi R Jonnalagadda; Barbara Lohman-Payne; Bess Sorensen; Elizabeth Maleche Obimbo; Dalton Wamalwa; Grace C John-Stewart
Journal:  Pediatr Infect Dis J       Date:  2014-04       Impact factor: 2.129
  8 in total
  4 in total

1.  A Randomized Controlled Trial of Isoniazid to Prevent Mycobacterium tuberculosis Infection in Kenyan Human Immunodeficiency Virus-Exposed Uninfected Infants.

Authors:  Sylvia M LaCourse; Barbra A Richardson; John Kinuthia; A J Warr; Elizabeth Maleche-Obimbo; Daniel Matemo; Lisa M Cranmer; Jerphason Mecha; Jaclyn N Escudero; Thomas R Hawn; Grace John-Stewart
Journal:  Clin Infect Dis       Date:  2021-07-15       Impact factor: 9.079

2.  Bacille Calmette-Guérin Vaccine Strain Modulates the Ontogeny of Both Mycobacterial-Specific and Heterologous T Cell Immunity to Vaccination in Infants.

Authors:  Agano Kiravu; Sophia Osawe; Anna-Ursula Happel; Trishana Nundalall; Jerome Wendoh; Sophie Beer; Nobomi Dontsa; Olatogni Berenice Alinde; Sikiratu Mohammed; Pam Datong; D William Cameron; Kenneth Rosenthal; Alash'le Abimiku; Heather B Jaspan; Clive M Gray
Journal:  Front Immunol       Date:  2019-10-01       Impact factor: 7.561

3.  The Etiology of Pneumonia in HIV-uninfected South African Children: Findings From the Pneumonia Etiology Research for Child Health (PERCH) Study.

Authors:  David P Moore; Vicky L Baillie; Azwifarwi Mudau; Jeannette Wadula; Tanja Adams; Shafeeka Mangera; Charl Verwey; Christine Prosperi; Melissa M Higdon; Meredith Haddix; Laura L Hammitt; Daniel R Feikin; Katherine L O'Brien; Maria Deloria Knoll; David R Murdoch; Eric A F Simões; Shabir A Madhi
Journal:  Pediatr Infect Dis J       Date:  2021-09-01       Impact factor: 2.129

4.  Infant TB Infection Prevention Study (iTIPS): a randomised trial protocol evaluating isoniazid to prevent M. tuberculosis infection in HIV-exposed uninfected children.

Authors:  Sylvia M LaCourse; Barbra A Richardson; John Kinuthia; A J Warr; Elizabeth Maleche-Obimbo; Daniel Matemo; Lisa M Cranmer; Jaclyn N Escudero; Thomas R Hawn; Grace C John-Stewart
Journal:  BMJ Open       Date:  2020-01-21       Impact factor: 2.692
  4 in total

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