| Literature DB >> 29460914 |
E I Chukanova1, A S Chukanova1.
Abstract
The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and absence of side-effects even during the long-term treatment.Entities:
Keywords: alpha-lipoic acid; diabetes mellitus; diabetic neuropathies; endothelial dysfunction; oxidative stress
Mesh:
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Year: 2018 PMID: 29460914 DOI: 10.17116/jnevro201811811103-109
Source DB: PubMed Journal: Zh Nevrol Psikhiatr Im S S Korsakova ISSN: 1997-7298