Literature DB >> 29460914

[Alpha-lipoic acid in the treatment of diabetic polyneuropathy].

E I Chukanova1, A S Chukanova1.   

Abstract

The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and absence of side-effects even during the long-term treatment.

Entities:  

Keywords:  alpha-lipoic acid; diabetes mellitus; diabetic neuropathies; endothelial dysfunction; oxidative stress

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Substances:

Year:  2018        PMID: 29460914     DOI: 10.17116/jnevro201811811103-109

Source DB:  PubMed          Journal:  Zh Nevrol Psikhiatr Im S S Korsakova        ISSN: 1997-7298


  2 in total

1.  Alpha-lipoic acid could attenuate the effect of chemerin-induced diabetic nephropathy progression.

Authors:  Hong Zhang; Jiawei Mu; Jinqiu Du; Ying Feng; Wenhui Xu; Mengmeng Bai; Huijuan Zhang
Journal:  Iran J Basic Med Sci       Date:  2021-08       Impact factor: 2.699

2.  Lipoic Acid Decreases the Expression of Poly ADP-Ribose Polymerase and Inhibits Apoptosis in Diabetic Rats.

Authors:  Jingfang Chen; Qiang Li
Journal:  Diabetes Metab Syndr Obes       Date:  2020-05-20       Impact factor: 3.168

  2 in total

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