| Literature DB >> 29460727 |
Ayok M Tembei1,2, Jonas A Kengne-Ouaffo1,2, Elvis A Ngoh1,2, Bonekeh John3, Theobald M Nji4,1, Kebede Deribe5,6, Peter Enyong1, Theresa Nkuo-Akenji2, Gail Davey6, Samuel Wanji1,2.
Abstract
Leprosy and podoconiosis (podo) are neglected tropical diseases that cause severe disfigurement and disability, and may lead to catastrophic health expenditure and hinder economic development of affected persons and households. This study compared economic costs of both diseases on affected households with unaffected neighboring households in the Northwest Region (N.W.R.) of Cameroon. A matched comparative cross-sectional design was used enrolling 170 households (43 podo case households, 41 podo control households, 43 leprosy case households, and 43 leprosy control households) from three health districts in the N.W.R. Direct treatment costs for podo averaged 142 United State dollar (USD), compared with zero for leprosy (P < 0.001). This was also reflected in the proportion of annual household income consumed (0.4 versus 0.0, respectively, P < 0.001). Both diseases caused considerable reductions in working days (leprosy 115 versus podo 135 days. P for comparison < 0.001). The average household income was considerably lower in podo-affected households than unaffected households (410 versus 913 USD, P = 0.01), whereas income of leprosy-affected households was comparable to unaffected households (329 versus 399 USD, P = 0.23). Both leprosy and podo cause financial burdens on affected households, but those on podo-affected families are much greater. These burdens occur through direct treatment costs and reduced ability to work. Improved access to public health interventions for podo including prevention, morbidity management and disability prevention are likely to result in economic returns to affected families. In Cameroon, one approach to this would be through subsidized health insurance for these economically vulnerable households.Entities:
Mesh:
Year: 2018 PMID: 29460727 PMCID: PMC5899508 DOI: 10.4269/ajtmh.17-0931
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345
Categories for cost assessment
| Cost type | Cost category | Definition |
|---|---|---|
| Direct costs (out-of-pocket payments) | Biomedical expenses and hygiene costs | These costs were related to patients’ personal hygiene when taking care of the wounds (e.g., bleach and soap to wash bandages and clothing), irregular expenses for extra medication (e.g., for pain relief), and official fees during treatment. |
| Food, lodging, and transportation costs | Food costs included extra meals taken at local food stands by patients or caretakers. Transportation costs refer to the costs of transport for the patient, caretaker(s), and other household members when traveling to and from the hospital to visit the hospitalized patient or when seeking care. Lodging costs included extra rent in the location of the hospital for caretakers. | |
| Miscellaneous costs | These included a variety of non-systematic costs such as extra phone calls, debts to community workgroups due to illness, gifts to hospitalized patients, extra food from home to hospital, etc. | |
| Indirect costs (disability) | Productivity loss | Productivity loss was based on the calculation of the individual’s (patient and/or caretaker) earnings per calendar year and the percentage of these earnings that was lost because of the morbidity and disability time caused by illness episode or caretaking. |
Figure 1.Case–control study design showing health cost assessment method for podoconiosis and leprosy. Common diseases referred to diseases of which every household within the community was likely to observe an episode yearly. This figure appears in color at www.ajtmh.org.
Basic characteristics of participants
| Variable | Category | Podoconiosis participants ( | Leprosy participants ( | ||||
|---|---|---|---|---|---|---|---|
| Cases (%) | Controls (%) | Cases (%) | Controls (%) | ||||
| Gender | Male | 22 (51.2) | 22 (53.7) | NS | 22 (51.2) | 22 (51.2) | NS |
| Female | 21 (48.8) | 19 (46.3) | 21 (48.8) | 21 (48.8) | |||
| Age (years) | Mean (SD) | 59 (16.8) | 58 (17.3) | NA | 61 (16) | 61 (15.6) | NA |
| Range (Min.–Max.) | 57 (30–87) | 59 (26–85) | 60 (27–87) | 65 (25–90) | |||
| Literacy level | Higher | 3 (7.0) | 4 (10.0) | NS | 1 (2.3) | 1 (2.4) | NS |
| Secondary | 4 (9.3) | 3 (7.5) | 3 (7.0) | 6 (14.6) | |||
| Primary | 23 (53.5) | 29 (72.5) | 25 (58.1) | 23 (56.1) | |||
| None | 13 (30.2) | 4 (10.0) | 14 (32.6) | 11 (26.8) | |||
| Marital status | Single | 3 (7.0) | 3 (7.3) | NS | 10 (23.3) | 7 (16.7) | NS |
| Married/in union | 23 (53.5) | 30 (73.2) | 15 (34.9) | 26 (61.9) | |||
| Divorced/separated | 3 (7.0) | 1 (2.4) | 6 (14.0) | 0 (0.0) | |||
| Widowed | 14 (32.6) | 7 (17.1) | 12 (27.9) | 9 (21.4) | |||
| Religion | Christian | 43 (100) | 41 (100) | NA | 43 (100) | 42 (100) | NA |
Max. = maximium; Min. = minimium; n = total sample size; NA = not applicable; NS = not significant; SD = standard deviation; % = percentage. Level of significance; P value <0.05.
Household income, direct and indirect cost of common household diseases
| Variable | Leprosy respondents ( | Podoconiosis respondents ( | |||||
|---|---|---|---|---|---|---|---|
| Median ± SD | Median ± SD | ||||||
| Household income | Controls | 43 | 399 (1,146) | NS | 41 | 913 (1,120) | 0.005 |
| Cases | 43 | 329 (556) | 43 | 410 (1,194) | |||
| Total direct cost common diseases | Controls | 43 | 76 ± 91 | NS | 40 | 142 ± 189 | NS |
| Cases | 43 | 36 ± 75 | 42 | 147 ± 183 | |||
| Total | 86 | 56 ± 83 | – | 82 | 145 ± 186 | – | |
| Cost burden (fraction of household income consumed) (%) | Controls | 43 | 12 ± 78 | NS | 41 | 13 ± 55 | 0.006 |
| Cases | 43 | 6 ± 81 | 42 | 33 ± 348 | |||
| Mean | Mean | ||||||
| Working days lost to common diseases | Controls | 43 | 23 ± 19 | 41 | 47 ± 53 | NS | |
| Cases | 43 | 36 ± 37 | 41 | 58 ± 52 | |||
| Median | Median | ||||||
| Total indirect cost of common diseases | Controls | 43 | 11 ± 26 | NS | 41 | 18 ± 38 | NS |
| Cases | 43 | 6 ± 14 | 41 | 12 ± 24 | |||
| Total | 86 | 9 ± 20 | – | 82 | 15 ± 31 | – | |
n = sample size; NS = not significant; SD = standard deviation; % = percentage.
Significant.
All cost was measured in United State dollar.
Direct and indirect cost of podo and leprosy on affected households‡
| Cost categories | Leprosy (median ± SD) | Podo (median ± SD) | |
|---|---|---|---|
| Direct medical costs | 0.00 ± 8 | 137 ± 488 | < 0.001 |
| Direct nonmedical costs | 0.00 ± 0.13 | 9 ± 24 | < 0.001 |
| Miscellaneous | 0.00 ± 0.34 | 9 ± 18 | < 0.001 |
| Total direct costs | 0.00 ± 8 | 142 ± 517 | < 0.001 |
| Amount borrowed | 0.00 ± 8 | 34 ± 489 | < 0.001 |
| Mean ± SD | Mean ± SD | ||
| Working days lost | 115 ± 62 | 135 ± 106 | < 0.001 |
| Median ± SD | Median ± SD | ||
| Total indirect costs | 26 ± 45 | 40 ± 124 | NS |
| Annual economic cost (direct and indirect) of podo/leprosy | 26 ± 45 | 203 ± 559 | < 0.001 |
| Fraction of household income consumed yearly (cost burden) (%) | 0 ± 4 | 40 ± 303 | < 0.001 |
NS = not significant; Podo = podoconiosis; SD = standard deviation; % = percentage.
Significant.
All costs were measured in United States dollar.
Sample size was 86 (43 podo and 43 leprosy).