| Literature DB >> 2946044 |
B F Roy, J W Rose, H F McFarland, D E McFarlin, D L Murphy.
Abstract
Human IgG specific for beta-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression demonstrated plasma IgG highly reactive with human beta-endorphin, while four other subjects (two with depression and two randomly selected blood donors) had intermediate reactivity. The recognition site for beta-endorphin was retained by F(ab')2 fragments.Entities:
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Year: 1986 PMID： 2946044 PMCID： PMC387007 DOI： 10.1073/pnas.83.22.8739
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205