Literature DB >> 29460015

[Immuno-, radio-, and chemotherapeutic studies in head and neck cancer : Highlights of the ASCO Annual Meeting 2017].

P J Schuler1, A von Witzleben2, J Doescher2, B Wollenberg3, A Dietz4, T K Hoffmann2.   

Abstract

In recent years, immunotherapy has been shown to be a promising approach for the treatment of various tumor entities. Due to further pharmacological developments and new studies, the checkpoint inhibitors have now arrived in the clinic. To date, patients with cancers in the head and neck region have benefited from these agents as part of a palliative therapy. Current clinical trials are testing other indications for the checkpoint inhibitors as monotherapy or in combination with other therapeutic approaches. The following article summarizes the highlights of the American Society of Clinical Oncology (ASCO) Annual Meeting.

Entities:  

Keywords:  ASCO; Cell cyle checkpoints; Genetic structures; Genome; Immunotherapy

Mesh:

Year:  2018        PMID: 29460015     DOI: 10.1007/s00106-018-0482-9

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  9 in total

1.  Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck.

Authors:  Jay S Cooper; Thomas F Pajak; Arlene A Forastiere; John Jacobs; Bruce H Campbell; Scott B Saxman; Julie A Kish; Harold E Kim; Anthony J Cmelak; Marvin Rotman; Mitchell Machtay; John F Ensley; K S Clifford Chao; Christopher J Schultz; Nancy Lee; Karen K Fu
Journal:  N Engl J Med       Date:  2004-05-06       Impact factor: 91.245

2.  Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial.

Authors:  Tanguy Y Seiwert; Barbara Burtness; Ranee Mehra; Jared Weiss; Raanan Berger; Joseph Paul Eder; Karl Heath; Terrill McClanahan; Jared Lunceford; Christine Gause; Jonathan D Cheng; Laura Q Chow
Journal:  Lancet Oncol       Date:  2016-05-27       Impact factor: 41.316

3.  CANCER IMMUNOLOGY. The "cancer immunogram".

Authors:  Christian U Blank; John B Haanen; Antoni Ribas; Ton N Schumacher
Journal:  Science       Date:  2016-05-06       Impact factor: 47.728

4.  Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity.

Authors:  Xiangdong Liu; Niu Shin; Holly K Koblish; Gengjie Yang; Qian Wang; Kathy Wang; Lynn Leffet; Michael J Hansbury; Beth Thomas; Mark Rupar; Paul Waeltz; Kevin J Bowman; Padmaja Polam; Richard B Sparks; Eddy W Yue; Yanlong Li; Richard Wynn; Jordan S Fridman; Timothy C Burn; Andrew P Combs; Robert C Newton; Peggy A Scherle
Journal:  Blood       Date:  2010-03-02       Impact factor: 22.113

Review 5.  Response Evaluation in Head and Neck Oncology: Definition and Prediction.

Authors:  T K Hoffmann; P J Schuler; S Laban; R Grässlin; M Beer; A J Beer; U Friebe-Hoffmann; L Bullinger; P Möller; T Wiegel
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  2017-02-24       Impact factor: 1.538

6.  Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses.

Authors:  Manish J Butte; Mary E Keir; Theresa B Phamduy; Arlene H Sharpe; Gordon J Freeman
Journal:  Immunity       Date:  2007-07-12       Impact factor: 31.745

7.  Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck.

Authors:  Robert L Ferris; George Blumenschein; Jerome Fayette; Joel Guigay; A Dimitrios Colevas; Lisa Licitra; Kevin Harrington; Stefan Kasper; Everett E Vokes; Caroline Even; Francis Worden; Nabil F Saba; Lara C Iglesias Docampo; Robert Haddad; Tamara Rordorf; Naomi Kiyota; Makoto Tahara; Manish Monga; Mark Lynch; William J Geese; Justin Kopit; James W Shaw; Maura L Gillison
Journal:  N Engl J Med       Date:  2016-10-08       Impact factor: 91.245

8.  PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cells.

Authors:  Katarzyna Karwacz; Christopher Bricogne; Douglas MacDonald; Frederick Arce; Clare L Bennett; Mary Collins; David Escors
Journal:  EMBO Mol Med       Date:  2011-08-10       Impact factor: 12.137

Review 9.  Functional Expression of Programmed Death-Ligand 1 (B7-H1) by Immune Cells and Tumor Cells.

Authors:  Rachel M Gibbons Johnson; Haidong Dong
Journal:  Front Immunol       Date:  2017-08-10       Impact factor: 7.561

  9 in total
  1 in total

Review 1.  [Oncoimmunology in old age].

Authors:  M C Wigand; S Jeske; J Hahn; J Doescher; S Laban; T K Hoffmann; P J Schuler
Journal:  HNO       Date:  2020-03       Impact factor: 1.284

  1 in total

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