Literature DB >> 2945921

Alveolar cavitational osteopathosis. Manifestations of an infectious process and its implication in the causation of chronic pain.

E J Ratner, B Langer, M L Evins.   

Abstract

A recently discovered oral disease process of infectious origin, characterized by nonradiographically detectable, hollow, pathologic, alveolar cavitational lesions of significant size, is described. This oral infectious disease process, termed alveolar cavitational osteopathosis, is causally implicated not only in the genesis of certain craniofacial pain syndromes, among them idiopathic trigeminal neuralgia and atypical facial pain, but also in chronic pain syndromes remote from the craniofacial region including the back, chest, arms, legs and cervical areas. A diagnostic process is presented which serves to define the locus of nonradiographically detectable alveolar cavitational osteopathosis and correlates a given pathological site to a given area of pain. Comprehensive schematics have been developed defining the pain pathways emanating from the oral cavity and their specific relationship to sites of perceived pain both in the craniofacial region and other areas of the body. The treatment modality described serves to induce bone growth within the cavitational lesions, resulting in the subsequent eradication of the cavity. The abolition of osteopathosis results in significant or total disappearance of pain symptomatology.

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Year:  1986        PMID: 2945921     DOI: 10.1902/jop.1986.57.10.593

Source DB:  PubMed          Journal:  J Periodontol        ISSN: 0022-3492            Impact factor:   6.993


  6 in total

1.  Chemokine RANTES/CCL5 as an unknown link between wound healing in the jawbone and systemic disease: is prediction and tailored treatments in the horizon?

Authors:  Johann Lechner; Volker von Baehr
Journal:  EPMA J       Date:  2015-05-06       Impact factor: 6.543

2.  Peripheral Neuropathic Facial/Trigeminal Pain and RANTES/CCL5 in Jawbone Cavitation.

Authors:  Johann Lechner; Volker von Baehr
Journal:  Evid Based Complement Alternat Med       Date:  2015-06-11       Impact factor: 2.629

3.  Aseptic-avascular osteonecrosis: local "silent inflammation" in the jawbone and RANTES/CCL5 overexpression.

Authors:  Johann Lechner; Sabine Schuett; Volker von Baehr
Journal:  Clin Cosmet Investig Dent       Date:  2017-11-09

4.  The vitamin D receptor and the etiology of RANTES/CCL-expressive fatty-degenerative osteolysis of the jawbone: an interface between osteoimmunology and bone metabolism.

Authors:  Johann Lechner; Jürgen Aschoff; Tatjana Rudi
Journal:  Int J Gen Med       Date:  2018-04-27

5.  Titanium implants and silent inflammation in jawbone-a critical interplay of dissolved titanium particles and cytokines TNF-α and RANTES/CCL5 on overall health?

Authors:  Johann Lechner; Sammy Noumbissi; Volker von Baehr
Journal:  EPMA J       Date:  2018-06-08       Impact factor: 6.543

6.  Neuralgia-inducing cavitational osteonecrosis - Fact or myth, the debate persists.

Authors:  Yazad R Gandhi
Journal:  Natl J Maxillofac Surg       Date:  2019-11-12
  6 in total

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