Literature DB >> 29459206

Structure-based design and biological evaluation of inhibitors of the pseudomonas aeruginosa heme oxygenase (pa-HemO).

Dongdong Liang1, Elizabeth Robinson1, Kellie Hom1, Wenbo Yu1, Nam Nguyen1, Yue Li2, Qianshou Zong3, Angela Wilks4, Fengtian Xue5.   

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Year:  2018        PMID： 29459206      PMCID： PMC5851869          DOI： 10.1016/j.bmcl.2018.02.027

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


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  35 in total

1.  Privileged scaffolds or promiscuous binders: a comparative study on rhodanines and related heterocycles in medicinal chemistry.

Authors:  Thomas Mendgen; Christian Steuer; Christian D Klein
Journal:  J Med Chem       Date:  2012-01-11       Impact factor: 7.446

2.  Identification of two heme-binding sites in the cytoplasmic heme-trafficking protein PhuS from Pseudomonas aeruginosa and their relevance to function.

Authors:  Darci R Block; Gudrun S Lukat-Rodgers; Kenton R Rodgers; Angela Wilks; Mehul N Bhakta; Ila B Lansky
Journal:  Biochemistry       Date:  2007-11-20       Impact factor: 3.162

3.  New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays.

Authors:  Jonathan B Baell; Georgina A Holloway
Journal:  J Med Chem       Date:  2010-04-08       Impact factor: 7.446

4.  Keeping an eye on P. aeruginosa.

Authors:  Susannah J Salter
Journal:  Nat Rev Microbiol       Date:  2014-12-31       Impact factor: 60.633

5.  Predictive compound accumulation rules yield a broad-spectrum antibiotic.

Authors:  Michelle F Richter; Bryon S Drown; Andrew P Riley; Alfredo Garcia; Tomohiro Shirai; Riley L Svec; Paul J Hergenrother
Journal:  Nature       Date:  2017-05-10       Impact factor: 49.962

6.  Homologues of neisserial heme oxygenase in gram-negative bacteria: degradation of heme by the product of the pigA gene of Pseudomonas aeruginosa.

Authors:  M Ratliff; W Zhu; R Deshmukh; A Wilks; I Stojiljkovic
Journal:  J Bacteriol       Date:  2001-11       Impact factor: 3.490

7.  Requirement of the Pseudomonas aeruginosa tonB gene for high-affinity iron acquisition and infection.

Authors:  H Takase; H Nitanai; K Hoshino; T Otani
Journal:  Infect Immun       Date:  2000-08       Impact factor: 3.441

8.  Metabolic flux of extracellular heme uptake in Pseudomonas aeruginosa is driven by the iron-regulated heme oxygenase (HemO).

Authors:  Kylie D Barker; Katalin Barkovits; Angela Wilks
Journal:  J Biol Chem       Date:  2012-04-09       Impact factor: 5.157

9.  Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections.

Authors:  Stefanie Wagner; Roman Sommer; Stefan Hinsberger; Cenbin Lu; Rolf W Hartmann; Martin Empting; Alexander Titz
Journal:  J Med Chem       Date:  2016-02-18       Impact factor: 7.446

10.  Structural basis for novel delta-regioselective heme oxygenation in the opportunistic pathogen Pseudomonas aeruginosa.

Authors:  Jonathan Friedman; Latesh Lad; Huiying Li; Angela Wilks; Thomas L Poulos
Journal:  Biochemistry       Date:  2004-05-11       Impact factor: 3.162
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  3 in total

1.  Ranking Reversible Covalent Drugs: From Free Energy Perturbation to Fragment Docking.

Authors:  Han Zhang; Wenjuan Jiang; Payal Chatterjee; Yun Luo
Journal:  J Chem Inf Model       Date:  2019-02-27       Impact factor: 4.956

Review 2.  Metallotherapeutics development in the age of iron-clad bacteria.

Authors:  Garrick Centola; Fengtian Xue; Angela Wilks
Journal:  Metallomics       Date:  2020-12-23       Impact factor: 4.526

3.  Recombinant Production of Biliverdin IXβ and δ Isomers in the T7 Promoter Compatible Escherichia coli Nissle.

Authors:  Elizabeth A Robinson; Nicole Frankenberg-Dinkel; Fengtian Xue; Angela Wilks
Journal:  Front Microbiol       Date:  2021-12-08       Impact factor: 5.640
  3 in total

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