Literature DB >> 2945894

Antigen-specific, MHC nonrestricted T helper cell-induced B cell activation.

S M Friedman, J A Jover, E K Chartash, M K Crow.   

Abstract

We used a cloned, TNP-specific, MHC-restricted, human Th cell line, E-11, and an assay of cognate Th-B cell interaction, BLAST-2 antigen expression on the B cell surface, to investigate the functional nature of the Th cell antigen receptor. We observed that E-11 induces BLAST-2 expression by resting B cells in a hapten-dependent, hapten-specific, but MHC nonrestricted manner. The implication of these results for the Th cell receptor are discussed.

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Year:  1986        PMID： 2945894      PMCID： PMC2188441          DOI： 10.1084/jem.164.5.1773

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  12 in total

Review 1.  Immune response (Ir) genes of the murine major histocompatibility complex.

Authors:  R H Schwartz
Journal:  Adv Immunol       Date:  1986       Impact factor: 3.543

2.  BLAST-2 [EBVCS], an early cell surface marker of human B cell activation, is superinduced by Epstein Barr virus.

Authors:  D A Thorley-Lawson; L M Nadler; A K Bhan; R T Schooley
Journal:  J Immunol       Date:  1985-05       Impact factor: 5.422

Review 3.  The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition.

Authors:  M Kronenberg; G Siu; L E Hood; N Shastri
Journal:  Annu Rev Immunol       Date:  1986       Impact factor: 28.527

4.  Cooperativity in antigen binding as a potential element in Tc cell recognition.

Authors:  R V Blanden; D B Gill; R Zidovetzki; I Pecht
Journal:  Mol Immunol       Date:  1980-07       Impact factor: 4.407

5.  Cloned allospecific human helper T cell lines induce an MHC-restricted proliferative response by resting B cells.

Authors:  D Goldberg; A Green; A B Gottlieb; M K Crow; A Lewison; S M Friedman
Journal:  J Immunol       Date:  1985-08       Impact factor: 5.422

6.  T-cell hybridoma specific for a cytochrome c peptide: specific antigen binding and interleukin 2 production.

Authors:  S Carel; C Bron; G Corradin
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

7.  Allospecific human T cell lines and clones which mediate HLA-DR restricted helper activity.

Authors:  S M Friedman; G S Thompson; M A Principato
Journal:  J Immunol       Date:  1982-12       Impact factor: 5.422

8.  The use of avidin-biotin interaction in immunoenzymatic techniques.

Authors:  J L Guesdon; T Ternynck; S Avrameas
Journal:  J Histochem Cytochem       Date:  1979-08       Impact factor: 2.479

9.  Binding of antigen in the absence of histocompatibility proteins by arsonate-reactive T-cell clones.

Authors:  A Rao; W W Ko; S J Faas; H Cantor
Journal:  Cell       Date:  1984-04       Impact factor: 41.582

10.  A cloned major histocompatibility complex-restricted trinitrophenyl-reactive human helper T cell line that activates B cell subsets via two distinct pathways.

Authors:  M A Principato; G S Thompson; S M Friedman
Journal:  J Exp Med       Date:  1983-11-01       Impact factor: 14.307
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