Emily Frith1, Paul D Loprinzi2. 1. Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS 38677, United States. 2. Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS 38677, United States. Electronic address: paulloprinzi@gmail.com.
Abstract
OBJECTIVE: We evaluated the specific association between physical activity and cognitive function among a national sample of the broader U.S. adult population with a family history of Alzheimer's disease. METHODS: Data from the 1999-2002 National Health and Nutrition Examination Survey (NHANES) were used to identify 219 older adults, ages 60-85, with a family history of Alzheimer's disease. The Digit Symbol Substitution Test (DSST) was used to assess cognitive function, with physical activity assessed via a validated questionnaire. RESULTS: In an unadjusted model, older adults, who had at least one blood relative with Alzheimer's disease, had greater cognitive function when meeting MVPA guidelines in comparison to their inactive counterparts (β=9.6; 95% CI: 4.6-14.7; P=0.001). After adjustments, results were attenuated, but still statistically significant (8.5; 95% CI: 4.0-13.0; P=0.001). CONCLUSION: In this national sample of individuals at risk for Alzheimer's disease, meeting physical activity guidelines was associated with higher cognitive function.
OBJECTIVE: We evaluated the specific association between physical activity and cognitive function among a national sample of the broader U.S. adult population with a family history of Alzheimer's disease. METHODS: Data from the 1999-2002 National Health and Nutrition Examination Survey (NHANES) were used to identify 219 older adults, ages 60-85, with a family history of Alzheimer's disease. The Digit Symbol Substitution Test (DSST) was used to assess cognitive function, with physical activity assessed via a validated questionnaire. RESULTS: In an unadjusted model, older adults, who had at least one blood relative with Alzheimer's disease, had greater cognitive function when meeting MVPA guidelines in comparison to their inactive counterparts (β=9.6; 95% CI: 4.6-14.7; P=0.001). After adjustments, results were attenuated, but still statistically significant (8.5; 95% CI: 4.0-13.0; P=0.001). CONCLUSION: In this national sample of individuals at risk for Alzheimer's disease, meeting physical activity guidelines was associated with higher cognitive function.
Authors: Juan Du; Xiaomei Chen; Li Xi; Beibei Jiang; Jun Ma; Guangsheng Yuan; Ahmad Hassan; Erkang Fu; Yumei Huang Journal: Int J Environ Res Public Health Date: 2022-08-14 Impact factor: 4.614