Waldo Sepulveda1, Jose H Ochoa2, Daniel Cafici3, Amy E Wong4, Federico Badano5, Elena Andreeva6, Elena Y Andreeva7. 1. FETALMED-Fetal Imaging Unit, Maternal-Fetal Diagnostic Center, Santiago, Chile. 2. DIAGNUS-Prenatal Diagnosis and Teaching Center, Cordoba, Argentina. 3. Grupo Medico Alem, Buenos Aires, Argentina. 4. 4Department of Maternal-Fetal Medicine, Palo Alto Medical Foundation, Mountain View, CA, USA. 5. FB Diagnostico por Imagenes, Gualeguaychu, Entre Rios, Argentina. 6. Moscow Regions Research Institute of Obstetrics and Gynecology, Medical-Genetics Department, Moscow, Russia. 7. Center of Reproductive Medicine, Irkutsk, Russia.
Abstract
INTRODUCTION: Congenital splenic cysts are a rare cause of abdominal cystic masses in the fetus. We describe nine cases of this condition, the largest reported experience to date. A review of the literature for similar cases was also performed. METHODS: Cases of congenital splenic cyst were collected from three prenatal diagnostic centers and from a dedicated website of prenatal diagnosis. Information regarding clinical and sonographic findings was obtained by reviewing ultrasound reports and medical records. An electronic search of the Pubmed/MEDLINE database for similar cases, with subsequent manual cross-referencing, was performed and the relevant information from the articles was retrieved. RESULTS: A total of nine cases were added to the currently existing literature of 32 cases. In all but one of our cases, the prenatal detection of the splenic cyst was made in the third trimester, with a median gestational age at diagnosis of 30 weeks (range 22-37). The splenic cyst was confirmed after delivery in all but one case, which was lost to follow up. Postnatal sonographic examinations performed in the remaining eight cases showed that the cyst increased in size in two (25%), was stable in size in one (12%), decreased in size in one (12%), and completely regressed in the other four cases (50%). No complications associated with the cysts were reported in the infants. CONCLUSIONS: Congenital splenic cyst appears to be a benign condition with no known risk of perinatal complications. Nevertheless, differential diagnosis with other fetal cystic masses of the left upper abdominal quadrant and postnatal sonographic follow up to monitor the size of the cyst are important issues to be considered in the perinatal management of these cases.
INTRODUCTION: Congenital splenic cysts are a rare cause of abdominal cystic masses in the fetus. We describe nine cases of this condition, the largest reported experience to date. A review of the literature for similar cases was also performed. METHODS: Cases of congenital splenic cyst were collected from three prenatal diagnostic centers and from a dedicated website of prenatal diagnosis. Information regarding clinical and sonographic findings was obtained by reviewing ultrasound reports and medical records. An electronic search of the Pubmed/MEDLINE database for similar cases, with subsequent manual cross-referencing, was performed and the relevant information from the articles was retrieved. RESULTS: A total of nine cases were added to the currently existing literature of 32 cases. In all but one of our cases, the prenatal detection of the splenic cyst was made in the third trimester, with a median gestational age at diagnosis of 30 weeks (range 22-37). The splenic cyst was confirmed after delivery in all but one case, which was lost to follow up. Postnatal sonographic examinations performed in the remaining eight cases showed that the cyst increased in size in two (25%), was stable in size in one (12%), decreased in size in one (12%), and completely regressed in the other four cases (50%). No complications associated with the cysts were reported in the infants. CONCLUSIONS: Congenital splenic cyst appears to be a benign condition with no known risk of perinatal complications. Nevertheless, differential diagnosis with other fetal cystic masses of the left upper abdominal quadrant and postnatal sonographic follow up to monitor the size of the cyst are important issues to be considered in the perinatal management of these cases.
Authors: J Badía Barnusel; E Moltó Santonja; J Posa Bernades; R Permanyer Fuster; R Turul Gener; C Durán Feliubadaló; C Martín Martínez; F Mellado Navarro Journal: An Esp Pediatr Date: 1990-04
Authors: Robert Dankovcik; Peter Urdzik; Igor Lazar; Andrea Gresova; Jozef Radonak; Jan E Jirasek; Eduard Kucera; Jaroslav Feyereisl; Marek Dudas Journal: Fetal Diagn Ther Date: 2009-09-11 Impact factor: 2.587