Renata Pecotic1, Ivana Pavlinac Dodig2, Maja Valic2, Tea Galic3, Linda Lusic Kalcina2, Natalija Ivkovic4, Zoran Dogas2. 1. Department of Neuroscience and Split Sleep Medicine Center, University of Split School of Medicine, Soltanska 2, 21 000, Split, Croatia. renata.pecotic@mefst.hr. 2. Department of Neuroscience and Split Sleep Medicine Center, University of Split School of Medicine, Soltanska 2, 21 000, Split, Croatia. 3. Study of Dental Medicine and Department of Neuroscience, University of Split School of Medicine, Split, Croatia. 4. Split Sleep Medicine Center, University Hospital Split and University of Split School of Medicine, Split, Croatia.
Abstract
STUDY OBJECTIVES: We prospectively investigated the effects of continuous positive airway pressure (CPAP) on long-term cognitive and psychomotor performances, and excessive daytime sleepiness in severe obstructive sleep apnea (OSA) patients. METHODS: A total of 40 patients were recruited and 23 patients with severe OSA fully completed the study protocol to investigate the effects of CPAP therapy on psychomotor performance at 1, 3, and 6 months and 1 year following initiation of the therapy. Psychomotor CRD-series tests measuring reaction times of light stimulus perception, solving simple arithmetic operations, and complex psychomotor limb coordination, were used in this study. The data collected following CPAP therapy were compared to baseline values prior to the CPAP treatment for each patient. RESULTS: All of the measured variables improved following CPAP treatment. However, the most pronounced effect was observed in improvement of reaction times to complex psychomotor limb coordination test (p < 0.05). Self-reported evaluation of excessive daytime sleepiness measured by Epworth Sleepiness Scale (ESS) showed significant decrease from 10.0 ± 1.1 before to 3.5 ± 0.5 (p < 0.001), after 1 year on CPAP therapy. CONCLUSIONS: The CPAP therapy improved cognitive and psychomotor performance on CRD-series tests with the most significant improvement observed in complex psychomotor limb coordination of severe OSA patients.
STUDY OBJECTIVES: We prospectively investigated the effects of continuous positive airway pressure (CPAP) on long-term cognitive and psychomotor performances, and excessive daytime sleepiness in severe obstructive sleep apnea (OSA) patients. METHODS: A total of 40 patients were recruited and 23 patients with severe OSA fully completed the study protocol to investigate the effects of CPAP therapy on psychomotor performance at 1, 3, and 6 months and 1 year following initiation of the therapy. Psychomotor CRD-series tests measuring reaction times of light stimulus perception, solving simple arithmetic operations, and complex psychomotor limb coordination, were used in this study. The data collected following CPAP therapy were compared to baseline values prior to the CPAP treatment for each patient. RESULTS: All of the measured variables improved following CPAP treatment. However, the most pronounced effect was observed in improvement of reaction times to complex psychomotor limb coordination test (p < 0.05). Self-reported evaluation of excessive daytime sleepiness measured by Epworth Sleepiness Scale (ESS) showed significant decrease from 10.0 ± 1.1 before to 3.5 ± 0.5 (p < 0.001), after 1 year on CPAP therapy. CONCLUSIONS: The CPAP therapy improved cognitive and psychomotor performance on CRD-series tests with the most significant improvement observed in complex psychomotor limb coordination of severe OSA patients.
Authors: Stuart F Quan; Ron Wright; Carol M Baldwin; Kristine L Kaemingk; James L Goodwin; Tracy F Kuo; Alfred Kaszniak; Lori L Boland; Elise Caccappolo; Richard R Bootzin Journal: Sleep Med Date: 2006-07-03 Impact factor: 3.492
Authors: Maja Rogić Vidaković; Joško Šoda; Ana Jerković; Benjamin Benzon; Karla Bakrač; Silvia Dužević; Igor Vujović; Mario Mihalj; Renata Pecotić; Maja Valić; Angela Mastelić; Maximilian Vincent Hagelien; Marina Zmajević Schőnwald; Zoran Đogaš Journal: Nat Sci Sleep Date: 2020-08-06
Authors: Ivana Pavlinac Dodig; Dona Krišto; Linda Lušić Kalcina; Renata Pecotić; Maja Valić; Zoran Đogaš Journal: Croat Med J Date: 2020-04-30 Impact factor: 1.351