Literature DB >> 29452968

Analysis and description of disease-specific quality of life in patients with anal fistula.

Manuel Ferrer-Márquez1, Natalia Espínola-Cortés2, Ángel Reina-Duarte2, José Granero-Molina3, Cayetano Fernández-Sola3, José Manuel Hernández-Padilla4.   

Abstract

INTRODUCTION: In patients diagnosed with anal fistula, knowing the quality of life specifically related to the disease can help coloproctology specialists to choose the most appropriate therapeutic strategy for each case. The aim of our study is to analyzse and describe the factors related to the specific quality of life in a consecutive series of patients diagnosed with anal fistula.
METHODS: Observational, cross-sectional study carried out from March 2015 to February 2017. All patients were assessed in the colorectal surgery unit of a hospital in southeast of Spain. After performing an initial anamnesis and a physical examination, patients diagnosed with anal fistula completed the Quality of Life in Ppatients with Anal Fistula Questionnaire (QoLAF-Q). This questionnaire specifically measures quality of life in people with anal fistula and its score range is the following: zero impact = 14 points, limited impact = 15 to 28 points, moderate impact = 29 to 42 points, high impact = 43 to 56 points, and very high impact = 57 to 70 points.
RESULTS: A total of 80 patients were included. The median score obtained in the questionnaire for the sample studied was 34.00 (range=14-68). Statistically significant differences between patients with "primary anal fistula" (n=65) and "recurrent anal fistula" (n=15) were observed (mean rank=42.96 vs. mean rank=29.83, p=0.048). Furthermore, an inverse proportion (P=.016) between "time with clinical symptoms" and "impact on quality of life" was found (<6 months: mean rank = 45.55; 6-12 months: mean rank = 44.39; 1-2 years: mean rank = 37.83; 2-5 years: mean rank = 22; >5 years: mean rank = 19.00). There were no statistically significant differences (P=.149) between quality of life amongst patients diagnosed with complex (mean rank = 36.13) and simple fistulae (mean rank = 43.59).
CONCLUSIONS: Anal fistulae exert moderate-high impact on patients' quality of life. "Shorter time experiencing clinical symptoms" and the "presence of primary fistula" are factors that can be associated with worse quality of life.
Copyright © 2018 AEC. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Anal fistula; Calidad de vida; Fístula anal; QoLAF-Q; Quality of life

Mesh:

Year:  2018        PMID: 29452968     DOI: 10.1016/j.ciresp.2017.12.003

Source DB:  PubMed          Journal:  Cir Esp (Engl Ed)        ISSN: 2173-5077


  2 in total

1.  Living with cryptoglandular anal fistula: a qualitative investigation of the patient's experience through semi-structured patient interviews.

Authors:  Nusrat Iqbal; Astrid J H M Machielsen; Stephanie O Breukink; Rebecca Woodcock; Gillian Kane; Laith Alrubaiy; Ugo Grossi; Merel L Kimman; Phil J Tozer
Journal:  Qual Life Res       Date:  2022-02-17       Impact factor: 3.440

Review 2.  Do Patient-Reported Quality-of-Life (QoL) Scales Provide an Adequate Assessment of Patients with Cryptoglandular Anal Fistulae? A Systematic Review of Measurement Instruments and Their Content Validity.

Authors:  Nusrat Iqbal; Rishi Shah; Laith Alrubaiy; Phil Tozer
Journal:  Clin Pract       Date:  2022-08-15
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.