| Literature DB >> 29452164 |
Luca De Sabato1, Philippe Lemey2, Bram Vrancken3, Lebana Bonfanti4, Letizia Ceglie4, Gabriele Vaccari5, Ilaria Di Bartolo6.
Abstract
The near-complete genomic sequences of two hepatitis E virus (HEV) strains, detected from feces of infected pigs, were obtained. Phylogenetic analysis and p-distance comparisons of the complete coding regions showed a close relationship to the French swine strain FR-SHEV3c-like detected in 2006 (p-distance value 0.101), belonging to HEV-3 but not assigned to any known subtype. The three HEV sequences showed, relatively high nucleotide distances (p-distance >0.129) compared to the other defined HEV subtype references and unclassified strains. The HEV classification criteria and the high sequence similarity suggest that these strains can be assigned to a putative novel subtype of genotype 3, HEV-3l.Entities:
Keywords: Complete genome; Genotype 3; Hepatitis E virus; Next generation sequencing; Subtype; Swine
Mesh：
Substances：
Year: 2018 PMID： 29452164 DOI： 10.1016/j.virusres.2018.02.010
Source DB: PubMed Journal: Virus Res ISSN： 0168-1702 Impact factor: 3.303