Paul F Rühle1, Gerhart Klein2,3, Tatiana Rung4, Hong Tiep Phan4, Claudia Fournier5, Rainer Fietkau1, Udo S Gaipl1, Benjamin Frey1. 1. a Department of Radiation Oncology , Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg , Erlangen , Germany. 2. b Practice for Cardiology , Bad Steben , Germany. 3. c Health Resort Research Association , Bad Steben , Germany. 4. d Klinik Frankenwarte , Bad Steben , Germany. 5. e GSI Helmholtzzentrum für Schwerionenforschung , Darmstadt , Germany.
Abstract
OBJECTIVES: Therapies with low doses of radon have beneficial effects on patients suffering from chronic painful degenerative and inflammatory diseases. We already showed that this is accompanied by systemic immune modulations. We here focus on pain-reducing effects of very low doses of radon by adding carbon dioxide water and its impact on heart rate variability (HRV), blood pressure and free radicals. METHODS: 97 of 103 patients receiving radon spa (1.200 Bq/l at 34 °C or 600 Bq/l, 1 g/l CO2 at 34 °C) were monitored before and at three different time points after therapy. Individual pain perception was analyzed and the capability to process radicals. At each time point, the hypertensive patients (n = 46) were examined over 24 h for blood pressure and HRV. RESULTS: Long-term pain reduction was observed in the majority of patients. A modulation of superoxide dismutase was identified, presumably representing a priming effect for lowering radiation stress. Further, lowering of blood pressure, especially in those patients who additionally received carbon dioxide, was seen. Radon did in particular impact on HRV implying lasting relaxation effects. CONCLUSION: Radon/carbon dioxide spa efficiently reduces pain. In particular, patients simultaneously suffering from painful and cardiovascular diseases should be treated by combination of radon and CO2.
OBJECTIVES: Therapies with low doses of radon have beneficial effects on patients suffering from chronic painful degenerative and inflammatory diseases. We already showed that this is accompanied by systemic immune modulations. We here focus on pain-reducing effects of very low doses of radon by adding carbon dioxidewater and its impact on heart rate variability (HRV), blood pressure and free radicals. METHODS: 97 of 103 patients receiving radon spa (1.200 Bq/l at 34 °C or 600 Bq/l, 1 g/l CO2 at 34 °C) were monitored before and at three different time points after therapy. Individual pain perception was analyzed and the capability to process radicals. At each time point, the hypertensivepatients (n = 46) were examined over 24 h for blood pressure and HRV. RESULTS: Long-term pain reduction was observed in the majority of patients. A modulation of superoxide dismutase was identified, presumably representing a priming effect for lowering radiation stress. Further, lowering of blood pressure, especially in those patients who additionally received carbon dioxide, was seen. Radon did in particular impact on HRV implying lasting relaxation effects. CONCLUSION: Radon/carbon dioxidespa efficiently reduces pain. In particular, patients simultaneously suffering from painful and cardiovascular diseases should be treated by combination of radon and CO2.
Authors: Miriam Kullmann; Paul F Rühle; Alexandra Harrer; Anna Donaubauer; Ina Becker; Renate Sieber; Gerhart Klein; Claudia Fournier; Rainer Fietkau; Udo S Gaipl; Benjamin Frey Journal: Radiat Environ Biophys Date: 2018-11-19 Impact factor: 1.925
Authors: M Gaisberger; J Fuchs; M Riedl; S Edtinger; R Reischl; G Grasmann; B Hölzl; F Landauer; H Dobias; F Eckstein; M Offenbächer; M Ritter; M Winklmayr Journal: Int J Biometeorol Date: 2021-03-01 Impact factor: 3.787
Authors: Andreas Maier; Julia Wiedemann; Felicitas Rapp; Franziska Papenfuß; Franz Rödel; Stephanie Hehlgans; Udo S Gaipl; Gerhard Kraft; Claudia Fournier; Benjamin Frey Journal: Int J Mol Sci Date: 2020-12-30 Impact factor: 5.923
Authors: Anna-Jasmina Donaubauer; Lisa Deloch; Ina Becker; Rainer Fietkau; Benjamin Frey; Udo S Gaipl Journal: Int J Mol Sci Date: 2020-09-02 Impact factor: 5.923
Authors: Markus Ritter; Bertram Hölzl; Martin Gaisberger; Antje van der Zee-Neuen; Victoria Strobl; Heidemarie Dobias; Julia Fuchs; Johannes Untner; Wolfgang Foisner; Martina Knapp; Sebastian Edtinger; Martin Offenbächer Journal: BMC Musculoskelet Disord Date: 2022-08-03 Impact factor: 2.562