| Literature DB >> 29450217 |
Janelle Aby1, Juliann Lipps Kim2.
Abstract
Objective. The purpose of this study is to describe the range and frequency of cutaneous lumbosacral and coccygeal findings encountered during the newborn examination in a population of apparently healthy babies, to determine if the prevalence of these findings is associated with race/ethnicity, and to report the frequency of co-occurrence of low-risk cutaneous findings. Methods. Lumbosacral physical findings of 1121 infants were documented on well newborns at least 35 weeks or greater gestational age under the authors' care. The overall frequency of each physical finding was tabulated in addition to determining whether frequencies varied by race/ethnicity. Co-occurrence of the most common physical findings was also examined. Results. Of 1096 infants included in the study, 24.8% had deviated or duplicated gluteal creases, 15.6% had dimples, and 24.7% had lumbosacral and/or coccygeal hairiness. All racial/ethnic groups had double to quadruple the risk of lumbosacral hair when compared with Caucasians. A total of 44.1% of study infants had lumbosacral/coccygeal slate-grey patches, which were least common in Caucasians. Seven infants had coccygeal skin tags, and 14 infants had lumbosacral vascular macules. Thirty-one percent had more than 1 cutaneous lumbosacral finding present, 24.8% had 2 findings, and 6.2% had 3 or more findings. Conclusion. Coccygeal dimples, increased lumbosacral and/or coccygeal hair, deviations and/or duplications of the gluteal crease, and lumbosacral slate-grey patches are common in healthy newborns and vary by race/ethnicity. Eleven percent of study infants had 2 or more low-risk cutaneous findings excluding slate-grey patches. Distinction between low-risk and common versus high-risk findings is important when deciding which patients need further evaluation.Entities:
Keywords: dimple; gluteal crease; lumbosacral; newborn; spinal dysraphism
Year: 2018 PMID: 29450217 PMCID: PMC5808970 DOI: 10.1177/2333794X18756133
Source DB: PubMed Journal: Glob Pediatr Health ISSN: 2333-794X
Figure 1.Photographs of commonly noted lumbosacral cutaneous physical examination findings. A. Single, deviated gluteal crease with dimple. B. Duplicated gluteal crease. C. Small but visible concentration of coccygeal hair. D. Notable increase of both sacral and coccygeal hair.
Distribution of Lumbosacral Cutaneous Physical Examination Findings by Race-Ethnicity.
| Characteristics | Total Population, n (%) | Caucasian, n (%) | Hispanic, n (%) | Asian/Pacific Islander, n (%) | African American, n (%) | Other, n (%) | |
|---|---|---|---|---|---|---|---|
| All subjects | 1096 | 260 (23.7%) | 507 (46.3%) | 280 (25.5%) | 29 (2.6%) | 20 (1.8%) | |
| Infant sex | <.01 | ||||||
| Female | 508 (46.4) | 136 (52.3) | 235 (46.4) | 122 (43.6) | 5 (17.2) | 10 (50.0) | |
| Male | 588 (53.6) | 124 (47.7) | 272 (53.6) | 158 (56.4) | 24 (82.8) | 10 (50.0) | |
| Gluteal crease | <.01 | ||||||
| Single, straight crease | 826 (75.4) | 189 (72.7) | 397 (78.3) | 204 (72.9) | 19 (65.5) | 17 (85.0) | |
| Single, deviated crease | 91 (8.3) | 33 (12.7) | 28 (5.5) | 27 (9.6) | 1 (3.4) | 2 (10.0) | |
| Duplicated crease | 179 (16.3) | 38 (14.6) | 82 (16.2) | 49 (17.5) | 9 (31.0) | 1 (5.0) | |
| Coccygeal and/or sacral dimples | .29 | ||||||
| No dimple | 921 (84.0) | 214 (82.3) | 427 (84.2) | 242 (86.4) | 24 (82.8) | 14 (70.0) | |
| Shallow dimple | 146 (13.3) | 36 (13.8) | 70 (13.8) | 31 (11.1) | 4 (13.8) | 5 (25.0) | |
| Deep dimple | 14 (1.3) | 6 (2.3) | 3 (0.6) | 4 (1.4) | 0 | 1 (5.0) | |
| Multiple dimples | 15 (1.4) | 4 (1.5) | 7 (1.4) | 3 (1.1) | 1 (3.4) | 0 | |
| Slate-grey macules (Mongolian spots) | 483 (44.1) | 25 (9.6) | 260 (51.3) | 169 (60.4) | 19 (65.5) | 10 (50.0) | <.01 |
| Increased hair | 271 (24.7) | 23 (8.8) | 149 (29.4) | 85 (30.4) | 6 (20.7) | 8 (40.0) | <.01 |
| Vascular macules | 14 (1.3) | 8 (3.1) | 5 (1.0) | 1 (0.4) | 0 | 0 | .10 |
| Coccygeal skin tags | 7 (0.6) | 2 (0.8) | 2 (0.4) | 2 (0.7) | 1 (3.4) | 0 | .29 |
| Number of physical findings per patient[ | .19 | ||||||
| No findings | 492 (44.9) | 136 (52.3) | 221 (43.6) | 117 (41.8) | 11 (37.9) | 7 (35.0) | |
| One finding | 482 (44.0) | 101 (38.8) | 229 (45.2) | 128 (45.7) | 15 (51.7) | 9 (45.0) | |
| Two findings | 111 (10.1) | 20 (7.7) | 54 (10.7) | 31 (11.1) | 2 (6.9) | 4 (20.0) | |
| Three findings | 11 (1.0) | 3 (1.2) | 3 (0.6) | 4 (1.4) | 1 (3.4) | 0 |
Excluding slate-grey macules.
Relative Risk of Lumbosacral Physical Examination Findings Among Racial/Ethnic Groups[a,b].
| Characteristics | Total Population, n (%) | Caucasian, RR (95% CI) | Hispanic, RR (95% CI) | Asian/PI, RR (95% CI) | African American, RR (95% CI) | Other, RR (95% CI) |
|---|---|---|---|---|---|---|
| Single, deviated crease | 91 (8.3) | Reference |
| 0.80 (0.50-1.29) | 0.36 (0.05-2.50) | 0.71 (0.19-2.75) |
| Duplicated crease | 179 (16.3) | Reference | 1.02 (0.72-1.45) | 1.16 (0.79-1.70) | 1.91 (1.03-3.54) | 0.33 (0.05-2.28) |
| Dimples (any type) | 175 (16.0) | Reference | 0.89 (0.64-1.24) | 0.77 (0.52-1.14) | 0.97 (0.42-2.26) | 1.70 (0.83-3.48) |
| Slate-grey patches (Mongolian spots) | 483 (44.1) | Reference |
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| Increased hair | 271 (24.7) | Reference |
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| Vascular macules | 14 (1.3) | Reference | 0.35 (0.12-1.05) | 0.13 (0.02-1.04) |
[ |
[ |
| Two or more findings[ | 122 (11.1) | Reference | 1.27 (0.80-2.01) | 1.41 (0.86-2.32) | 1.15 (0.37-3.63) | 2.26 (0.87-5.90) |
Abbreviations: PI, Pacific Islander; RR, relative risk; CI, confidence interval.
Adjusted for gender.
Coccygeal skin tag data not reported because of small sample size.
Not reported because of small sample size.
Excluding slate-grey patches.
Bold type indicates findings with statistically significant racial differences.
Reported Radiology Results for All Study Infants Who Underwent Ultrasound of Spinal Contents.
| Patient | Physical Findings | Ultrasound Results |
|---|---|---|
| 1 | Duplicated gluteal crease | Normal |
| 2 | Duplicated gluteal crease | Normal |
| 3 | Duplicated gluteal crease | Normal |
| 4 | Duplicated gluteal crease | Normal |
| 5 | Duplicated gluteal crease | Normal |
| 6 | Simple dimple | Normal |
| 7 | Simple dimple | Normal |
| 8 | Simple dimple | Normal |
| 9 | Simple dimple | Normal |
| 10 | Deep dimple | Normal spinal contents. Unfused posterior elements of the distal spine. |
| 11 | Deep dimple | Normal spinal contents. Hypoechoic structure extends from the tip of the coccyx, possibly small tract which does not reach the skin surface. |
| 12 | Deep dimple | Conus slightly low at L2. |
| 13 | Two deep dimples | Conus low at L3. Small filar cyst (normal variant). |
| 14 | Coccygeal skin tag | Normal |
| 15 | Vascular macule | Normal |
| 16 | Vascular macule | Normal |
| 17 | Vascular macule | Normal |
| 18 | Vascular macule | Conus slightly low |
Co-Occurrence Between Lumbosacral Physical Examination Findings.
| Slate-Grey Patch | Increased Hair | Deviated or Duplicated Crease | Dimple | Vascular Macule | Skin Tag | |
|---|---|---|---|---|---|---|
| Slate-grey patch | ||||||
| Increased hair |
| |||||
| Deviated or duplicated crease | −0.08 |
| ||||
| Dimple |
| −0.04 | −0.05 | |||
| Vascular macule | −0.24 | −0.28 | 0.05 | 0.08 | ||
| Skin tag | 0.12 | 0.04 |
[ | −0.03 |
[ |
Not applicable because of small sample size.
P < .05. **P < .01.
Bold type indicates statisically significant correlations