Literature DB >> 29449043

The Verigene dilemma: gram-negative polymicrobial bloodstream infections and clinical decision making.

Kimberly C Claeys1, Emily L Heil2, Jason M Pogue3, Paul R Lephart4, J Kristie Johnson5.   

Abstract

Verigene Blood-Culture Gram-Negative (GN) results in rapid identification of key GNs in bloodstream infections. Its use clinically is limited by low sensitivity in polymicrobial GN infections and concerns for inappropriate antibiotic modification. In a retrospective review of 1003 blood culture sets, the incidence of missed GNs was infrequent, <4%, with the potential to negatively impact the management of GN BSIs in <2% of cases.
Copyright © 2018. Published by Elsevier Inc.

Entities:  

Keywords:  Bloodstream infection; Gram-negative; Microarray; Polymicrobial; Rapid diagnostics

Mesh：

Year:  2018        PMID： 29449043     DOI： 10.1016/j.diagmicrobio.2018.01.012

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  9 in total

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2.  An Antibiotic Stewardship Program Blueprint for Optimizing Verigene BC-GN within an Institution: a Tale of Two Cities.

Authors:  Jason M Pogue; Emily L Heil; Paul Lephart; J Kristie Johnson; Ryan P Mynatt; Hossein Salimnia; Kimberly C Claeys
Journal:  Antimicrob Agents Chemother       Date:  2018-04-26       Impact factor: 5.191

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8.  A Multicenter Clinical Study To Demonstrate the Diagnostic Accuracy of the GenMark Dx ePlex Blood Culture Identification Gram-Negative Panel.

Authors:  Donna M Wolk; Stephen Young; Natalie N Whitfield; Jennifer L Reid; Adam Thornberg; Karen C Carroll; Blake W Buchan; Thomas E Davis; Hossein Salimnia
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9.  Comparing the Clinical Utility of Rapid Diagnostics for Treatment of Bloodstream Infections Using Desirability of Outcome Ranking Approach for the Management of Antibiotic Therapy (DOOR-MAT).

Authors:  Kimberly C Claeys; Teri L Hopkins; Kathryn Schlaffer; Stephanie Hitchcock; Yunyun Jiang; Scott Evans; J Kristie Johnson; Surbhi Leekha
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  9 in total

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