Shree R Venkat1, Prasoon P Mohan1, Ripal T Gandhi2. 1. 1 University of Miami Miller School of Medicine, 1475 NW 12th Ave, Ste C080, Miami, FL 33136. 2. 2 Miami Cardiac and Vascular Institute, Miami, FL.
Abstract
OBJECTIVE: The objective of this article is to discuss the current treatment options for colorectal cancer (CRC) liver metastases and the role of ablation. CONCLUSION: A randomized control trial of ablation combined with chemotherapy showed improved overall survival compared with chemotherapy alone. Local recurrence rates are comparable to those associated with resection when ablative margins of more than 5 mm are achieved and target lesions are smaller than 3 cm. In patients with unresectable disease, ablation for curative intent should be considered.
OBJECTIVE: The objective of this article is to discuss the current treatment options for colorectal cancer (CRC) liver metastases and the role of ablation. CONCLUSION: A randomized control trial of ablation combined with chemotherapy showed improved overall survival compared with chemotherapy alone. Local recurrence rates are comparable to those associated with resection when ablative margins of more than 5 mm are achieved and target lesions are smaller than 3 cm. In patients with unresectable disease, ablation for curative intent should be considered.
Authors: Jesang Yu; Dong Hwan Kim; Jungbok Lee; Yong Moon Shin; Jong Hoon Kim; Sang Min Yoon; Jinhong Jung; Jin Cheon Kim; Chang Sik Yu; Seok-Byung Lim; In Ja Park; Tae Won Kim; Yong Sang Hong; Sun Young Kim; Jeong Eun Kim; Jin-Hong Park; So Yeon Kim Journal: Cancer Res Treat Date: 2021-10-13 Impact factor: 5.036
Authors: Susann-Cathrin Olthof; Daniel Wessling; Moritz T Winkelmann; Hansjörg Rempp; Konstantin Nikolaou; Rüdiger Hoffmann; Stephan Clasen Journal: Insights Imaging Date: 2022-03-21
Authors: Florentine E F Timmer; Bart Geboers; Sanne Nieuwenhuizen; Evelien A C Schouten; Madelon Dijkstra; Jan J J de Vries; M Petrousjka van den Tol; Martijn R Meijerink; Hester J Scheffer Journal: Cancers (Basel) Date: 2021-03-31 Impact factor: 6.639