Literature DB >> 29444461

Homology threading to generate RNA polymerase structures.

Yunsoo Kim1, Nils Benning2, Kasey Pham2, Nahid Baghdadi2, Gino Caruso2, Megan Colligan2, Allyssa Grayson2, Alexis Hurley2, Nick Ignatoski2, Sandra Mcclure2, Kelsey Mckaig2, Emily Neag2, Cole Showers2, Alexis Tangalos2, Jessica Vanells2, Kaillathe Padmanabhan3, Zachary F Burton4.   

Abstract

Homology threading is a powerful technology for generating structural models based on homologous structures. Here we use threading to generate four complex RNA polymerase models. The models appear to be as useful as x-ray crystal structures or cryo-electron microscopy structures to support research projects.
Copyright © 2018 Elsevier Inc. All rights reserved.

Keywords:  Drosophila melanogaster RNA polymerase II preinitiation complex; Homo sapiens RNA polymerase I and III; Homology modeling

Mesh:

Substances:

Year:  2018        PMID: 29444461     DOI: 10.1016/j.pep.2018.02.002

Source DB:  PubMed          Journal:  Protein Expr Purif        ISSN: 1046-5928            Impact factor:   1.650


  1 in total

1.  Aminoacyl-tRNA synthetase evolution and sectoring of the genetic code.

Authors:  Daewoo Pak; Yunsoo Kim; Zachary F Burton
Journal:  Transcription       Date:  2018-05-30
  1 in total

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