Literature DB >> 29444345

Completed Suicide Among Methamphetamine Users: A National Study.

Shane Darke1, Sharlene Kaye1,2, Johan Duflou1,3, Julia Lappin1,4.   

Abstract

All Australian cases of methamphetamine-related suicide (2009-2015) retrieved from the National Coronial Information System were examined to determine crude mortality rates, characteristics and circumstances of death, and blood toxicology. There were 300 cases, 18.2% of all methamphetamine-related deaths, and 1.6% of all completed suicides. The mean age was 33.1 years, and 77.0% were male. The crude mortality rate was 1.9 per 106 , with males having a significantly higher rate than females (2.9 vs. 0.9 per 106 ). A quarter were known to have previous suicide attempts, and a history of psychosis was noted in 12.3%. In 40.7% of cases, witnesses described the decedent as having been agitated and/or aggressive immediately prior to the incident. The vast majority (85.3%), and of both sexes (males 87.0%, females 79.7%), used violent methods. Hanging (70.3%) was overwhelmingly the most frequent method among both males (70.1%) and females (71.0%). Prescription medications were frequently present: hypnosedatives (23.6%), antidepressants (19.5%), and antipsychotics (8.4%). Self-poisoning cases were significantly more likely to have antidepressants (odds ratio: 4.2) and opioids (4.9) present, but less likely to have cannabis (0.3). Methamphetamine-related suicide makes a large contribution to methamphetamine-related death and represents a substantial clinical and public health problem.
© 2018 The American Association of Suicidology.

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Year:  2018        PMID: 29444345     DOI: 10.1111/sltb.12442

Source DB:  PubMed          Journal:  Suicide Life Threat Behav        ISSN: 0363-0234


  8 in total

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2.  Sex-Dependent Alterations in the mRNA Expression of Enzymes Involved in Dopamine Synthesis and Breakdown After Methamphetamine Self-Administration.

Authors:  Aaron E Miller; Atul P Daiwile; Jean Lud Cadet
Journal:  Neurotox Res       Date:  2022-07-14       Impact factor: 3.978

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4.  Sex-Specific Alterations in Dopamine Metabolism in the Brain after Methamphetamine Self-Administration.

Authors:  Atul P Daiwile; Patricia Sullivan; Subramaniam Jayanthi; David S Goldstein; Jean Lud Cadet
Journal:  Int J Mol Sci       Date:  2022-04-14       Impact factor: 6.208

5.  A Systematic Review of Risk Factors for Suicide Among Persons Living with HIV (1996-2020).

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Review 6.  Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts.

Authors:  Atul P Daiwile; Subramaniam Jayanthi; Jean Lud Cadet
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Review 7.  Dark Times: The Role of Negative Reinforcement in Methamphetamine Addiction.

Authors:  April C May; Robin L Aupperle; Jennifer L Stewart
Journal:  Front Psychiatry       Date:  2020-03-17       Impact factor: 4.157

8.  Methamphetamine Induces Systemic Inflammation and Anxiety: The Role of the Gut-Immune-Brain Axis.

Authors:  Majid Davidson; Marina Mayer; Amanda Habib; Niloufar Rashidi; Rhiannon Talia Filippone; Sarah Fraser; Monica D Prakash; Puspha Sinnayah; Kathy Tangalakis; Michael L Mathai; Kulmira Nurgali; Vasso Apostolopoulos
Journal:  Int J Mol Sci       Date:  2022-09-23       Impact factor: 6.208

  8 in total

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