| Literature DB >> 29443582 |
L B Schmitd1, C S Scanlon1, N J D'Silva1,2.
Abstract
Perineural invasion (PNI) is a mechanism of tumor dissemination that can provide a challenge to tumor eradication and that is correlated with poor survival. Squamous cell carcinoma, the most common type of head and neck cancer, has a high prevalence of PNI. This review provides an overview of clinical studies on the outcomes and factors associated with PNI in head and neck cancer and on findings on cancer-nerve crosstalk.Entities:
Keywords: galanin; metastasis; neoplasm recurrence; neurotrophic factors; prognosis; squamous cell carcinoma
Mesh:
Year: 2018 PMID: 29443582 PMCID: PMC6728584 DOI: 10.1177/0022034518756297
Source DB: PubMed Journal: J Dent Res ISSN: 0022-0345 Impact factor: 6.116