Literature DB >> 29441782

Soliseptide A, A Cyclic Hexapeptide Possessing Piperazic Acid Groups from Streptomyces solisilvae HNM30702.

Junfeng Wang1, Ziwen Cong1,2, Xiaolong Huang2, Chenxi Hou1, Weihao Chen1,3, Zhengchao Tu4, Dongyi Huang2, Yonghong Liu1,3.   

Abstract

Soliseptide A (1), a cyclic hexapeptide possessing piperazic acid groups, together with two known azalomycin derivatives (2 and 3) were isolated from Streptomyces solisilvae HNM30702. Their structures were determined through spectroscopic methods and single crystal X-ray diffraction analysis. Soliseptide A (1) possessed a cyclic hexapeptide core featured with two piperazic acid units rarely discovered in nature, and exhibited weak antibacterial and antiviral activities. Besides, compounds 2 and 3 displayed significant fungicidal effects.

Entities:  

Year:  2018        PMID： 29441782     DOI： 10.1021/acs.orglett.8b00142

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Bioactive Novel Indole Alkaloids and Steroids from Deep Sea-Derived Fungus Aspergillus fumigatus SCSIO 41012.

Authors:  Salendra Limbadri; Xiaowei Luo; Xiuping Lin; Shengrong Liao; Junfeng Wang; Xuefeng Zhou; Bin Yang; Yonghong Liu
Journal:  Molecules       Date:  2018-09-18       Impact factor: 4.411

2.  Perylenequione Derivatives with Anticancer Activities Isolated from the Marine Sponge-Derived Fungus, Alternaria sp. SCSIO41014.

Authors:  Xiaoyan Pang; Xiuping Lin; Pei Wang; Xuefeng Zhou; Bin Yang; Junfeng Wang; Yonghong Liu
Journal:  Mar Drugs       Date:  2018-08-14       Impact factor: 5.118

3.  Targeting autophagy peptidase ATG4B with a novel natural product inhibitor Azalomycin F4a for advanced gastric cancer.

Authors:  Lin Zhong; Bin Yang; Zhenhua Zhang; Junfeng Wang; Xiaojuan Wang; Yinfeng Guo; Weifeng Huang; Qianqian Wang; Guodi Cai; Fan Xia; Shengning Zhou; Shuai Ma; Yichu Nie; Jinping Lei; Min Li; Peiqing Liu; Wenbin Deng; Yonghong Liu; Fanghai Han; Junjian Wang
Journal:  Cell Death Dis       Date:  2022-02-18       Impact factor: 8.469

4.  Cyclic Peptides from the Soft Coral-Derived Fungus Aspergillus sclerotiorum SCSIO 41031.

Authors:  Jieyi Long; Yaqi Chen; Weihao Chen; Junfeng Wang; Xuefeng Zhou; Bin Yang; Yonghong Liu
Journal:  Mar Drugs       Date:  2021-12-10       Impact factor: 5.118
  4 in total

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