Literature DB >> 29441456

Knowledge, Attitude and Practice (KAP) Study of Pediatricians on Infantile Spasms.

Vamsi Krishna Vaddi1, Jitendra Kumar Sahu2, Sumeet R Dhawan1, Renu Suthar1, Naveen Sankhyan1.   

Abstract

OBJECTIVE: To investigate the knowledge, attitude, and practice of Infantile Spasms among pediatricians.
METHODS: A survey was carried out among pediatricians serving in Punjab, Haryana, Chandigarh, Himachal Pradesh and Delhi. The survey was done by Survey Monkey Software through emails by using a structured questionnaire between July 2016 and December 2017.
RESULTS: A total of 236 pediatricians responded to the survey. Most of the respondents (95.5%) correctly considered Infantile Spasms as a seizure type. The most preferred investigation was Electroencephalogram by 91.8% pediatricians; however, only 57.7% considered it to decide the treatment. Perinatal asphyxia was the most recognized etiology (60.7% pediatricians). For treatment of Infantile Spasms, 66.8% follow Nelson textbook of Pediatrics. Adrenocorticotropic hormone was the most preferred first choice drug by 40% pediatricians. Alternate anti-epileptic drug was considered by 60.9% pediatricians when there is no clinical response. Only 24% pediatricians considered treatment response as a complete cessation of spasms. Majority (90%) of pediatricians felt that there is a necessity for increased awareness and 62% pediatricians felt that available information was insufficient.
CONCLUSIONS: A substantial number of pediatricians lack precise knowledge on evidence-based practice of Infantile Spasms. In developing countries, where pediatricians provide the initial management of Infantile Spasms, there is need to empower them and develop simplified national guidelines/consensus statement for management of Infantile Spasms.

Entities:  

Keywords:  Epileptic spasms; Infantile epilepsy; KAP study; West syndrome

Mesh:

Substances:

Year:  2018        PMID: 29441456     DOI: 10.1007/s12098-018-2630-3

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  12 in total

Review 1.  The epidemiology and natural history of infantile spasms.

Authors:  L D Cowan; L S Hudson
Journal:  J Child Neurol       Date:  1991-10       Impact factor: 1.987

Review 2.  Infantile spasms--evidence based medical management.

Authors:  Jitendra Kumar Sahu
Journal:  Indian J Pediatr       Date:  2014-07-02       Impact factor: 1.967

3.  The effect of lead time to treatment and of age of onset on developmental outcome at 4 years in infantile spasms: evidence from the United Kingdom Infantile Spasms Study.

Authors:  Finbar J K O'Callaghan; Andrew L Lux; Katrina Darke; Stuart W Edwards; Eleanor Hancock; Anthony L Johnson; Colin R Kennedy; Richard W Newton; Christopher M Verity; John P Osborne
Journal:  Epilepsia       Date:  2011-06-10       Impact factor: 5.864

Review 4.  Efficacy of Treatments for Infantile Spasms: A Systematic Review.

Authors:  Ji Min Song; Jongsung Hahn; Se Hee Kim; Min Jung Chang
Journal:  Clin Neuropharmacol       Date:  2017 Mar/Apr       Impact factor: 1.592

5.  Profile of West syndrome in North Indian children.

Authors:  Pratibha Singhi; Munni Ray
Journal:  Brain Dev       Date:  2005-03       Impact factor: 1.961

Review 6.  A proposal for case definitions and outcome measures in studies of infantile spasms and West syndrome: consensus statement of the West Delphi group.

Authors:  Andrew L Lux; John P Osborne
Journal:  Epilepsia       Date:  2004-11       Impact factor: 5.864

7.  The Clinical Characteristics and Treatment Response in Children with West Syndrome in a Developing Country: A Retrospective Case Record Analysis.

Authors:  Sheffali Gulati; Puneet Jain; Lakshminarayanan Kannan; Rachna Sehgal; Biswaroop Chakrabarty
Journal:  J Child Neurol       Date:  2015-02-23       Impact factor: 1.987

8.  Hypsarrhythmia: variations on the theme.

Authors:  R A Hrachovy; J D Frost; P Kellaway
Journal:  Epilepsia       Date:  1984-06       Impact factor: 5.864

9.  Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort.

Authors:  Kelly G Knupp; Erin Leister; Jason Coryell; Katherine C Nickels; Nicole Ryan; Elizabeth Juarez-Colunga; William D Gaillard; John R Mytinger; Anne T Berg; John Millichap; Douglas R Nordli; Sucheta Joshi; Renée A Shellhaas; Tobias Loddenkemper; Dennis Dlugos; Elaine Wirrell; Joseph Sullivan; Adam L Hartman; Eric H Kossoff; Zachary M Grinspan; Lorie Hamikawa
Journal:  Epilepsia       Date:  2016-09-12       Impact factor: 5.864

10.  Clinical spectrum and treatment outcome of West Syndrome in children from Northern India.

Authors:  Jaya Shankar Kaushik; Bijoy Patra; Suvasini Sharma; Dinesh Yadav; Satinder Aneja
Journal:  Seizure       Date:  2013-05-02       Impact factor: 3.184

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  7 in total

1.  X-Linked ALG13 Gene Variant as a Cause of Epileptic Encephalopathy in Girls.

Authors:  Priyanka Madaan; Sandeep Negi; Rajni Sharma; Anupriya Kaur; Jitendra Kumar Sahu
Journal:  Indian J Pediatr       Date:  2019-08-23       Impact factor: 1.967

2.  Corticotrophin-ACTH in Comparison to Prednisolone in West Syndrome - A Randomized Study.

Authors:  Vykuntaraju K Gowda; Vindhya Narayanaswamy; Sanjay K Shivappa; Naveen Benakappa; Asha Benakappa
Journal:  Indian J Pediatr       Date:  2018-09-19       Impact factor: 1.967

Review 3.  Current Knowledge, Attitude and Practice (KAP) of Pediatricians on Infantile Spasms and the Way Forward.

Authors:  Prashant Jauhari
Journal:  Indian J Pediatr       Date:  2018-08-10       Impact factor: 1.967

4.  Review of West Syndrome: Concerns on Optimum Dose of Adrenocorticotrophic Hormone.

Authors:  Jitendra K Sahu; Vamsi Krishna Vaddi; Sandeep Negi
Journal:  Clin Drug Investig       Date:  2018-06       Impact factor: 2.859

5.  Topiramate as an Adjunct in the Management of West Syndrome.

Authors:  Pallavi L Nadig; Jitendra Kumar Sahu; Renu Suthar; Arushi Saini; Naveen Sankhyan
Journal:  Indian J Pediatr       Date:  2019-11-13       Impact factor: 1.967

6.  Management practices for West syndrome in South Asia: A survey study and meta-analysis.

Authors:  Priyanka Madaan; Prem Chand; Kyaw Linn; Jithangi Wanigasinghe; Mimi Lhamu Mynak; Prakash Poudel; Raili Riikonen; Amit Kumar; Pooja Dhir; Sandeep Negi; Jitendra Kumar Sahu
Journal:  Epilepsia Open       Date:  2020-08-11

7.  Financial Burden in Families of Children with West Syndrome.

Authors:  Dhvani Raithatha; Jitendra Kumar Sahu; Singanamalla Bhanudeep; Lokesh Saini; Shankar Prinja; Bhavneet Bharti; Priyanka Madaan; Saroj Kumar Rana; Sandeep Negi
Journal:  Indian J Pediatr       Date:  2021-05-26       Impact factor: 1.967

  7 in total

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