Literature DB >> 2944035

Quantitative autoradiographic localization of D-1 dopamine receptors in the rat brain: use of the iodinated ligand [125I]SCH 23982.

T M Dawson, P Barone, A Sidhu, J K Wamsley, T N Chase.   

Abstract

In vitro autoradiography was used to visualize [125I]SCH 23982 binding sites in rat brain. Labeling was concentrated in the caudate-putamen, accumbens nucleus, olfactory tubercle, substantia nigra pars reticulata and the entopeduncular nucleus. [125I]SCH 23982 labels predominantly D-1 receptors but also labels 5-HT2 receptors in certain areas of the brain. These findings may relate to the distribution of dopamine's cerebral loci of action on D-1 receptors.

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Year:  1986        PMID: 2944035     DOI: 10.1016/0304-3940(86)90499-4

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  12 in total

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2.  Autoradiographic localization of dopamine D 1 and D 2 receptors in the brain of several mammalian species.

Authors:  M Camps; P H Kelly; J M Palacios
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3.  Topography and collateralization of dopaminergic projections to primary motor cortex in rats.

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Review 5.  Motor learning in animal models of Parkinson's disease: Aberrant synaptic plasticity in the motor cortex.

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7.  Dopamine modulates the responsivity of mediodorsal thalamic cells recorded in vitro.

Authors:  A Lavin; A A Grace
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9.  Characterization of anti-peptide antibodies for the localization of D2 dopamine receptors in rat striatum.

Authors:  L D McVittie; M A Ariano; D R Sibley
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10.  Dynamic rewiring of neural circuits in the motor cortex in mouse models of Parkinson's disease.

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