| Literature DB >> 29439976 |
Yu Feng1,2, Lu Liu1,2, Alan McNally3, Zhiyong Zong4,2,5,6.
Abstract
In a carbapenem-resistant Escherichia coli clinical isolate of sequence type 167, two copies of blaNDM-5 were found on a 144,225-bp IncF self-transmissible plasmid of the F36:A4:B- type. Both blaNDM-5 genes were located in 11,065-bp regions flanked by two copies of IS26 The two regions were identical in sequence but were present at different locations on the plasmid, suggesting a duplication of the same region. This study highlights the complex genetic contexts of blaNDM-5.Entities:
Keywords: Escherichia coli; NDM; carbapenem resistance; carbapenemase; carbapenems; plasmids
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Year: 2018 PMID: 29439976 PMCID: PMC5923099 DOI: 10.1128/AAC.00110-18
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191