Literature DB >> 29439976

Coexistence of Two blaNDM-5 Genes on an IncF Plasmid as Revealed by Nanopore Sequencing.

Yu Feng1,2, Lu Liu1,2, Alan McNally3, Zhiyong Zong4,2,5,6.   

Abstract

In a carbapenem-resistant Escherichia coli clinical isolate of sequence type 167, two copies of blaNDM-5 were found on a 144,225-bp IncF self-transmissible plasmid of the F36:A4:B- type. Both blaNDM-5 genes were located in 11,065-bp regions flanked by two copies of IS26 The two regions were identical in sequence but were present at different locations on the plasmid, suggesting a duplication of the same region. This study highlights the complex genetic contexts of blaNDM-5.
Copyright © 2018 American Society for Microbiology.

Entities:  

Keywords:  Escherichia coli; NDM; carbapenem resistance; carbapenemase; carbapenems; plasmids

Mesh:

Substances:

Year:  2018        PMID: 29439976      PMCID: PMC5923099          DOI: 10.1128/AAC.00110-18

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  13 in total

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Review 3.  ISCR elements: novel gene-capturing systems of the 21st century?

Authors:  Mark A Toleman; Peter M Bennett; Timothy R Walsh
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4.  Detection of an Escherichia coli Sequence Type 167 Strain with Two Tandem Copies of blaNDM-1 in the Chromosome.

Authors:  Ping Shen; Maoli Yi; Ying Fu; Zhi Ruan; Xiaoxing Du; Yunsong Yu; Xinyou Xie
Journal:  J Clin Microbiol       Date:  2016-12-28       Impact factor: 5.948

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  7 in total

1.  Emergence of Carbapenem-Resistant Pseudomonas asiatica Producing NDM-1 and VIM-2 Metallo-β-Lactamases in Myanmar.

Authors:  Mari Tohya; Tatsuya Tada; Shin Watanabe; Kyoko Kuwahara-Arai; Khwar Nyo Zin; Ni Ni Zaw; May Yee Aung; San Mya; Khin Nyein Zan; Teruo Kirikae; Htay Htay Tin
Journal:  Antimicrob Agents Chemother       Date:  2019-07-25       Impact factor: 5.191

Review 2.  NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings.

Authors:  Wenjing Wu; Yu Feng; Guangmin Tang; Fu Qiao; Alan McNally; Zhiyong Zong
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Journal:  Antimicrob Agents Chemother       Date:  2020-10-20       Impact factor: 5.191

4.  Characterization of a novel bla NDM-5-harboring IncFII plasmid and an mcr-1-bearing IncI2 plasmid in a single Escherichia coli ST167 clinical isolate.

Authors:  Lijuan Xu; Ping Wang; Jing Cheng; Shangshang Qin; Weihong Xie
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5.  Nosocomial Outbreak of Carbapenemase-Producing Proteus mirabilis With Two Novel Salmonella Genomic Island 1 Variants Carrying Different bla NDM-1 Gene Copies in China.

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6.  Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDM.

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7.  Emergence of NDM-5-Producing Escherichia coli in a Teaching Hospital in Chongqing, China: IncF-Type Plasmids May Contribute to the Prevalence of bla NDM- 5.

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  7 in total

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