Literature DB >> 29439969

Comparative In Vitro Activity of Omadacycline against Dog and Cat Bite Wound Isolates.

Ellie J C Goldstein1,2, Diane M Citron3, Kerin L Tyrrell3, Eliza Leoncio3, C Vreni Merriam3.   

Abstract

Omadacycline was tested against 125 isolates recovered from infected cat and dog bites in humans. Its activity was similar to that of other compounds in the tetracycline class, and it was active against strains exhibiting tetracycline resistance. Against anaerobic isolates, resistance to tetracyclines was more prominent and omadacycline was the most active of the group. All isolates had omadacycline MICs of <1 μg/ml, with the exception of Eikenella corrodens, which showed reduced susceptibility to the entire tetracycline group.
Copyright © 2018 American Society for Microbiology.

Entities:  

Keywords:  Bacteroides pyogenes; Eikenella corrodens; Pasteurella; Prevotella heparinolytica; bite wounds; cellulitis; omadacycline; tetracyclines

Mesh：

Substances：

Year:  2018        PMID： 29439969      PMCID： PMC5914009          DOI： 10.1128/AAC.02551-17

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

Review 1.  Microbiology of animal bite wound infections.

Authors:  Fredrick M Abrahamian; Ellie J C Goldstein
Journal:  Clin Microbiol Rev       Date:  2011-04       Impact factor: 26.132

Review 2.  Omadacycline: development of a novel aminomethylcycline antibiotic for treating drug-resistant bacterial infections.

Authors:  Stephen Villano; Judith Steenbergen; Evan Loh
Journal:  Future Microbiol       Date:  2016-08-19       Impact factor: 3.165

3.  A randomized, evaluator-blind, phase 2 study comparing the safety and efficacy of omadacycline to those of linezolid for treatment of complicated skin and skin structure infections.

Authors:  Gary J Noel; Michael P Draper; Howard Hait; S Ken Tanaka; Robert D Arbeit
Journal:  Antimicrob Agents Chemother       Date:  2012-08-20       Impact factor: 5.191

4.  Bacteriology of human and animal bite wounds.

Authors:  E J Goldstein; D M Citron; B Wield; U Blachman; V L Sutter; T A Miller; S M Finegold
Journal:  J Clin Microbiol       Date:  1978-12       Impact factor: 5.948

5.  Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group.

Authors:  D A Talan; D M Citron; F M Abrahamian; G J Moran; E J Goldstein
Journal:  N Engl J Med       Date:  1999-01-14       Impact factor: 91.245
  5 in total
  5 in total

Review 1.  Omadacycline: A Review of the Clinical Pharmacokinetics and Pharmacodynamics.

Authors:  Keith A Rodvold; Rodrigo M Burgos; Xing Tan; Manjunath P Pai
Journal:  Clin Pharmacokinet       Date:  2020-04       Impact factor: 6.447

Review 2.  Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent.

Authors:  George G Zhanel; Jenine Esquivel; Sheryl Zelenitsky; Courtney K Lawrence; Heather J Adam; Alyssa Golden; Rachel Hink; Liam Berry; Frank Schweizer; Michael A Zhanel; Denice Bay; Philippe R S Lagacé-Wiens; Andrew J Walkty; Joseph P Lynch; James A Karlowsky
Journal:  Drugs       Date:  2020-02       Impact factor: 9.546

3.  What we actually know about the pathogenicity of Bacteroides pyogenes.

Authors:  Anna Majewska; Marta Kierzkowska; Dariusz Kawecki
Journal:  Med Microbiol Immunol       Date:  2021-05-02       Impact factor: 3.402

4.  Oral flora of stray dogs and cats in Algeria: Pasteurella and other zoonotic bacteria.

Authors:  Kahina Razali; Rachid Kaidi; Amine Abdelli; Mohamed Nabil Menoueri; Khatima Ait-Oudhia
Journal:  Vet World       Date:  2020-12-30

Review 5.  The Development of Third-Generation Tetracycline Antibiotics and New Perspectives.

Authors:  Aura Rusu; Emanuela Lorena Buta
Journal:  Pharmaceutics       Date:  2021-12-05       Impact factor: 6.321
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.