| Literature DB >> 29434356 |
Gerrit H J Kema1,2, Amir Mirzadi Gohari3,4, Lamia Aouini3, Hesham A Y Gibriel5, Sarah B Ware3,6, Frank van den Bosch7, Robbie Manning-Smith7, Vasthi Alonso-Chavez7, Joe Helps7, Sarrah Ben M'Barek8, Rahim Mehrabi9, Caucasella Diaz-Trujillo3,5, Elham Zamani10, Henk J Schouten3, Theo A J van der Lee3, Cees Waalwijk3, Maarten A de Waard5, Pierre J G M de Wit5, Els C P Verstappen3, Bart P H J Thomma5, Harold J G Meijer3, Michael F Seidl5.
Abstract
Host resistance and fungicide treatments are cornerstones of plant-disease control. Here, we show that these treatments allow sex and modulate parenthood in the fungal wheat pathogen Zymoseptoria tritici. We demonstrate that the Z. tritici-wheat interaction complies with the gene-for-gene model by identifying the effector AvrStb6, which is recognized by the wheat resistance protein Stb6. Recognition triggers host resistance, thus implying removal of avirulent strains from pathogen populations. However, Z. tritici crosses on wheat show that sex occurs even with an avirulent parent, and avirulence alleles are thereby retained in subsequent populations. Crossing fungicide-sensitive and fungicide-resistant isolates under fungicide pressure results in a rapid increase in resistance-allele frequency. Isolates under selection always act as male donors, and thus disease control modulates parenthood. Modeling these observations for agricultural and natural environments reveals extended durability of host resistance and rapid emergence of fungicide resistance. Therefore, fungal sex has major implications for disease control.Entities:
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Year: 2018 PMID： 29434356 DOI： 10.1038/s41588-018-0052-9
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330