| Literature DB >> 29433477 |
Yanping Li1, Wenyong Huang2, Aoyun Qiqige3, Hongwei Zhang4, Ling Jin2, Pula Ti5, Jennifer Yip6, Baixiang Xiao7,8.
Abstract
BACKGROUND: The aim of this cross-sectional study is to ascertain the prevalence and causes of blindness, visual impairment, uptake of cataract surgery among different ethnic groups in Xinjiang Uygur Autonomous Region, China.Entities:
Keywords: Cataract surgical coverage; China; Equity; Ethnical minority groups; Eye services; Prevalence of blindness; Xinjiang
Mesh:
Year: 2018 PMID: 29433477 PMCID: PMC5809952 DOI: 10.1186/s12886-018-0705-6
Source DB: PubMed Journal: BMC Ophthalmol ISSN: 1471-2415 Impact factor: 2.209
Fig. 1Map of China. The map picture was created by the user “Quigley” under the Creative Code “CC BY-SA 3.0” at the wiki website of https://en.wikipedia.org/wiki/Xinjiang. It has been credited and edited with study sites being marked
Subjects by ethnic group, and examination status, by age and gender
| Ethnicity | Population in study areas | People selected | People examined | Not available | Refused | Unable | Total examined | |||||||
| n | % | n | % | n | % | n | % | n | % | n | % | n | % | |
| Han | 641,783 | (46.2) | 1775 | 42.8 | 1712 | (96.5) | 45 | (2.5) | 8 | (0.5) | 10 | (0.6) | 1712 | 100 |
| Kazak | 551,318 | (39.7) | 1837 | (44.3)* | 1747 | (95.1) | 80 | (4.4)** | 6 | (0.3) | 4 | (0.2) | 1747 | 100 |
| Yugur | 51,467 | (3.7) | 108 | (2.6) | 105 | (97.2) | 3 | (2.8) | 0 | 0.0 | 0 | 0.0 | 105 | 100 |
| Other | 145,862 | (10.5) | 430 | (10.4) | 413 | (96.1) | 11 | (2.6) | 2 | (0.5) | 4 | (I0.9) | 413 | 100 |
| Total | 1,390,430 | (100) | 4150 | (100) | 3977 | (95.8) | 139 | (3.4) | 16 | (0.4) | 18 | (0.4) | 3977 | 100 |
| Male | Female | Total | ||||||||||||
| Age | Population in study areas | People Examined | Population in study areas | People Examined | Population in study areas | People Examined | ||||||||
| n | % | n | % | n | % | n | % | n | % | n | % | |||
| 50–59 years | 11,771 | 45.4 | 727 | 40.2 | 11,730 | 44.1 | 905 | 41.7 | 23,501 | 44.8 | 1632 | 41.0 | ||
| 60–69 years | 8495 | 32.8 | 585 | 32.3 | 8822 | 33.2 | 749 | 34.5 | 17,317 | 33.0 | 1334 | 33.5 | ||
| 70–79 years | 4675 | 18.0 | 381 | 21.1 | 5020 | 18.9 | 387 | 17.9 | 9695 | 18.5 | 768 | 19.3 | ||
| 80+ years | 985 | 3.8 | 116 | 6.4 | 1012 | 3.8 | 127 | 5.9 | 1997 | 3.8 | 243 | 6.1 | ||
| Total | 25,926 | 100 | 1809 | 100 | 26,584 | 100 | 2168 | 100 | 52,510 | 100 | 3977 | 100 | ||
*It seemed we selected less Han Chinese and more Khazak compared their proportion of total population in study areas (p < 0.5)
**p < 0.01 Khazak people had highest rate of “not available” as they were mostly nomadic
Sample and adjusted prevalence of blindness, severe (SVI), moderate (MVI) and early (EVI) visual impairment - bilateral PVA
| Sample results | Age and Gender Adjusted results | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Han | Kazak | Uygur | Other | Total | Males | Females | Total | |||||||||
| n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | |
| Blindness | 27 | 1.6 (1.1–2.3) | 40 | 2.3 (1.7–3.1) | 0 | 0 | 2 | 0.5 (0.1–1.9) | 69 | 1.7 (1.4–2.2) | 1976 | 1.3 (0.7–1.8) | 2033 | 1.3 (0.8–1.7) | 4009 | 1.3 (0.8–1.7) |
| Severe VI | 20 | 1.2 (0.8–1.8) | 16 | 0.9 (0.6–1.5) | 3 | 2.9 (0.9–8.5) | 10 | 2.4 (1.3–4.4) | 49 | 1.2 (0.9–1.6) | 1787 | 1.1 (0. 5–1.7) | 1551 | 1.0 (0.5–1.4) | 3338 | 1.1 (0.7–1.4) |
| Moderate VI | 70 | 4.1 (3.2–5.1) | 50 | 2.9 (2.2–3.8) | 7 | 6.7 (3.2–13.4) | 16 | 3.9 (2.4–6.2) | 143 | 3.6 (3.1–4.2) | 4701 | 3.0 (2.2–3.8) | 5000 | 3.1 (2.3–3.9) | 9701 | 3.1 (2.4–3.7) |
| Early VI | 126 | 7.4 (6.2–8.7) | 72 | 4.1 (3.3–5.2)* | 4 | 3.8 (1.4–9.8) | 24 | 5.8 (3.9–8.5) | 226 | 5.7 (5.0–6.4) | 6478 | 4.2 (3.0–5.3) | 9392 | 5.8 (4.7–7.0) | 15,870 | 5.0 (4.0–6.0) |
*EVI prevalence of Khazak people is significantly lower than that of Han Chinese * P < 0.01
Principal cause of blindness, Severe Visual Impairment (VI), Moderate (MVI) and Early Visual Impairment (EVI) in persons
| Blindness | Severe VI | Moderate VI | Early VI | |
|---|---|---|---|---|
| % | % | % | % | |
| 1. Uncorrected Refractive Error | 1.4% | 16.3% | 23.8% | 49.1% |
| 3. Cataract untreated | 65.2% | 34.7% | 34.3% | 23.0% |
| 4. Cataract surgical complications | 2.9% | 0.0% | 0.7% | 0.4% |
| 6. Non Trachomatous corneal opacity | 1.4% | 4.1% | 7.0% | 3.5% |
| 8. Myopic retinopathy | 8.7% | 12.2% | 4.9% | 2.7% |
| 9. Glaucoma | 4.3% | 0.0% | 2.1% | 1.3% |
| 10. Diabetic retinopathy | 2.9% | 4.1% | 2.1% | 0.9% |
| 11. ARMD | 4.3% | 18.4% | 17.5% | 13.3% |
| 12. Other posterior segment disease | 5.8% | 10.2% | 5.6% | 4.9% |
| 13. All other globe/CNS abnormalitiesa | 2.9% | 0.0% | 2.1% | 0.9% |
| Total | 100.0% | 100.0% | 100.0% | 100.00% |
| A. Treatable (1,2,3) | 66.7% | 51.0% | 58.0% | 72.1% |
| B. Preventable (PHC/PEC services) (5,6,7,8) | 10.1% | 16.3% | 11.9% | 6.2% |
| C. Preventable (Ophthalmic services) (4,9,10) | 10.1% | 4.1% | 4.9% | 2.7% |
| D. Avoidable (A + B + C) | 87.0% | 71.4% | 74.8% | 81.0% |
| E. Posterior segment causes (8,9,10,11,12) | 26.1% | 44.9% | 32.2% | 23.0% |
aAll other globe/CNS abnormalities: Microphthalmos, anophthalmos, enucleated eye, amblyopia
Cataract surgical coverage by visual acuity, gender and ethnicity (95% confidence interval)
| Sex(%) | Ethnicity(%) | ||||||
|---|---|---|---|---|---|---|---|
| Visual Acuity | Male | Female | Han | Khazak | Uygur | Other | Total |
| VA < 3/60 | 61.3(42.2–78.2) | 66.7(52.5–78.9) | 71.8(55.1–85.0) | 56.4(39.6–72.2) | 100 | 60.0(14.7–94.7) | 64.7(53.6–74.8) |
| VA < 6/60 | 50.0(34.2–65.8) | 61.0(47.4–73.5) | 57.1(42.2–71.2) | 52.3(36.7–67.5) | 100 | 60.0(14.7–94.7) | 56.4(46.2–66.3) |
| VA < 6/18 | 40.7(27.6–55.0) | 48.2(37.1–59.4) | 46.9(34.3–59.8) | 43.3(30.6–56.8) | 75(19.4–99.4) | 33.3(7.49–70.1) | 45.3(36.7–54.0) |
Barriers to cataract surgery – bilateral PVA < 6/18 due to cataract, n (%), (each person can select one or two barriers)
| Male | Female | Han | Khazak | Uygur | Other | Total | |
|---|---|---|---|---|---|---|---|
| n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | |
| Total | 68 | 95 | 78 | 66 | 2 | 17 | 163 |
| Need not felt | 18 (26.5) | 25 (26.3) | 22 (28.2) | 16 (24.2) | 2 (100.0) | 3 (17.7) | 43 (26.4) |
| Fear | 16 (23.5) | 17 (17.9) | 13 (16.7) | 17 (25.8) | 0 (0.0) | 3 (17.7) | 33 (20.3) |
| Cost | 4 (5.9) | 2 (2.1) | 2 (2.6) | 3 (4.6) | 0 (0.0) | 1 (5.9) | 6 (3.7) |
| Treatment denied by provider | 3 (4.4) | 12 (12.6) | 8 (10.3) | 6 (9.1) | 0 (0.0) | 1 (5.9) | 15 (9.2) |
| Unaware treatment is possible | 36 (52.9) | 44 (46.3) | 42 (53.9) | 26 (39.4) | 1 (50.0) | 11 (64.7) | 80 (49.1) |
| Cannot access treatment | 6 (8.8) | 25 (26.2)* | 13 (16.7) | 17 (25.8) | 0 (0.0) | 1 (5.9) | 31 (19.0) |
| Local reasons | 7 (10.3) | 9 (9.5) | 2 (2.6) | 13 (19.7)* | 0 (0.0) | 1 (5.9) | 16 (9.8) |
*P < 0.01
Proportion of subjects wearing glasses, by ethnic group comparing Han with other groups, n (%)
| Han ( | Khazak ( | Uygur ( | Others ( | Total ( | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Wearing glasses for any reason | 642 | 37.5% | 198 | (11.3%)* | 15 | 14.3%* | 100 | 24.2%* | 955 | 24.0% |
| Wearing distance glasses | 59 | 3.5% | 26 | (1.5%)* | 6 | 5.7% | 5 | 1.2%** | 96 | 2.4% |
| Wearing presbyopic glasses | 592 | 34.6% | 177 | (10.1%)* | 10 | 9.5%* | 96 | 23.2%* | 875 | 22.0% |
* p < 0.001 ** p < 0.05