| Literature DB >> 2943310 |
S Rawat, A Mathur, U C Chaturvedi.
Abstract
Intraperitoneal inoculation with Japanese encephalitis virus (JEV) induces the generation of T suppressor cells for delayed type hypersensitivity (Ts-DTH) in Swiss albino mice. The Ts-DTH are hydrocortisone resistant, partially sensitive to X-irradiation and the membrane phenotype of Ts cells is Ly I+. Ts-DTH suppression is mediated through the production of soluble suppressor factor (SF-DTH). SF-DTH is non-dialysable but passes through 450 nm filter and does not sediment after centrifugation at 100,000 g for 2 h; chromatography on Sephadex G-100 indicates an approximate molecular weight of 12,000.Entities:
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Year: 1986 PMID: 2943310 PMCID: PMC2013045
Source DB: PubMed Journal: Br J Exp Pathol ISSN: 0007-1021